Chdi Foundation, Inc.

Jonathan Bard

Celia Dominguez

John Wityak

Michael Edward Prime

Christopher John Brown

Daniel Clark-Frew

Peter David Johnson

Sarah Hayes

Samuel Coe

Thomas Martin Krülle

Alex Kiselyov

Paul Richard Giles

Sébastien René Gabriel Galan

Thomas Martin Krulle

Richard Waldron Marston

Matthew Robert Mills

Samantha Brown

Duane Higgins

Longbin Liu

Matthew Randolf Lee

Elise Luciennen Paulette Gadouleau

Daryl Simon Walter

Inaki Morao

Ian James Wigginton

Malcolm George Taylor

Elise Lucienne Paulette Gadouleau

Derek Alexander Weddell

Samantha Louise Jones Green

Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use.

Probes for imaging huntingtin protein

The present disclosure relates generally to compounds that simultaneously bind both mutant huntingtin protein (mHTT) and an ubiquitin E3 ligase and their use as therapeutic agents, for example, in treating diseases, such as neurodegenerative disorders caused by aggregation of mHTT.

Compounds for targeting mutant huntingtin protein and uses thereof

Probes for imaging Huntingtin protein

Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use. 

Provided are imaging agents comprising a compound of Formula (I), or a pharmaceutically acceptable salt thereof, and methods of their use. 

Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use 

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New York, NY, United States of America

Jonathan Bard