General Electric Company

Ge Medical Systems Global Technology Company, LLC

Current Lighting Solutions, LLC

Ge Marquette Medical Systems, Inc.

General Electric Healthcare

The United States of America, As Represented by the Secretary, Department of Health and Human Services

Jonathan Alan Murray

Ernst Wolfgang Stautner

Jan Henrik Ardenkjaer-Larsen

Patrick Lively Padgett

David Michael Hoffman

Thomas L Toth

Gary Robert Allen

Robert F Senzig

Thomas Clynne

Guy M Besson

Hui Hu

Erik Leeming Kvam

Rui Chen

Kevin Jeffrey Benner

Hui David He

Shankara Bonthu Reddy

Armin H Pfoh

John Jay Williams

Kevin James Vick

Paul C Schanen

Murali Krishna Cherukuri

Willi W Hampel

Thomas R Murray

George E Seidenschnur

Gary R Strong

Nallathamby Devasahayam

Basel H Taha

Qiuzhen Xue

Arnaud Comment

Timothy William Skloss

Marcelino Bernardo

Albert Po-Fu Chen

James Richard Trigger

William Allen Berezowitz

Jeffrey R Immelt

Jan Henrik Ardenkjaer Larsen

A general illumination lighting system and/or at least one targeted surface illumination lighting system. The general illumination lighting system including a general illuminating light source configured to generate light toward one or more surfaces or materials to inactivate one or more pathogens on the one or more surfaces or materials. The at least one targeted surface illumination lighting system including one or more targeted surface illuminating light sources that are integrated into or coupled to a plurality of devices, equipment, or fixtures. The one or more targeted surface illuminating light sources configured to generate targeted light toward one or more surfaces of the devices, equipment, or fixtures to inactivate one or more pathogens on the one or more surfaces. The light from the general illuminating light source and the one or more targeted surface illuminating light source including an inactivating portion having wavelengths in a range of 280 to 380 nanometers.

Light disinfection system and method

Methods and systems are provided for a sealing system for a dynamic nuclear polarization (DNP) system. In one embodiment, a system comprises: a reservoir including an inlet opening; an outer tube; and a tapered seal shaped to seal against the inlet opening and the outer tube, the tapered seal including: a first section removably coupleable to a second section; and a through-hole formed by a first plurality of inner surfaces of both the first section and the second section, the through-hole shaped to encircle the outer tube. In this way, the tapered seal may be coupled around the fluid passage without inserting a tip of the fluid passage through the through-hole of the tapered seal, and a sterility of the system may be maintained.

Systems and method for a dynamic seal assembly for a fluid delivery system

Methods and systems are provided for a sealing system for a dynamic nuclear polarization (DNP) system. In one embodiment, a system comprises: a reservoir including an inlet opening; an outer tube; and a tapered seal shaped to seal against the inlet opening and the outer tube, the tapered seal including: a first section removably coupleable to a second section; a through-hole formed by a first plurality of inner surfaces of both the first section and the second section, the through-hole shaped to encircle the outer tube; and a vacuum channel extending through, from an outer surface to an inner surface of the first plurality of inner surfaces, one of the first section and second section. In this way, the tapered seal may be coupled around the fluid passage without inserting a tip of the fluid passage through the through-hole of the tapered seal, thereby maintaining a sterility of the system.

A cooling system is provided. The cooling system is associated with a dynamic nuclear polarization system and configured to cool a sample to a temperature suitable for dynamic nuclear polarization to be carried out on the sample while the sample is in the cooling system. The cooling system includes a cryogenic chamber that includes a cryogenic fluid. The cooling system also includes a removable sample sleeve insertable within a portion of the cryogenic chamber. The removable sample sleeve is configured to define a sample path for the sample within the cryogenic chamber that is isolated from other parts of the cooling system.

Fluid path insert for a cryogenic cooling system

A system and method for transporting a hyperpolarized substance is disclosed. A transport vessel for transporting such a hyperpolarized substance includes a vessel housing, a chamber formed within the vessel housing that is configured to receive a container holding a hyperpolarized substance, and an electromagnet configured to generate a magnetic containment field about the chamber when a current is supplied thereto, the magnetic containment field comprising a homogeneous magnetic field. The transport vessel also includes a non-magnetic power source to supply the current to the electromagnet and a control circuit configured to selectively interrupt the supply of current to the electromagnet so as to control generation of the magnetic containment field, with the transport vessel being magnetically inert when the supply of current to the electromagnet is interrupted by the control circuit.

Hyperpolarized media transport vessel

A method to be used during a product development procedure wherein the procedure includes a series of consecutive development phases and the product includes at least two critical to quality characteristics (CTQs). The method is for generating a confidence matrix which can be used to increase a product sigma through product design. A user initially provides product limits and thereafter provides additional development information during each consecutive development phase. During at least two of the development phases and for each CTQ, development information is used to determine a quality factor which is indicative of the probability that the product will be within the specified limits. Also, for each CTQ, a confidence factor is identified which is indicative of the probability that the quality factor is accurate. Then, quality factors, CTQs and confidence factors are arranged such that the CTQs and factors are correlated.

Six sigma design method

In order to reduce bias associated with conventional ECG analysis, the present invention provides a method and apparatus to improve diagnosis of acute cardiac syndromes (ACS), such as acute myocardial infarction and acute cardiac ischemia (unstable angina), in specified groups of patients using ECG signals and automatic detection analysis. Specific criteria are developed and utilized based on a prespecified group selection for the particular patient. After identifying group membership for the particular patient, ECG data are acquired from a patient experiencing ACS symptoms. Known criteria typically used for assessing ACS are then modified for the particular group membership. Such criteria significantly reduce the bias found in a baseline group for which the known criteria were established. The invention is particularly useful in identifying an ACS, and the type of ACS, in females under the age of 60 where it has been found that the current critical ST threshold is too high to consistently identify an ACS in this subgroup.

Method and apparatus to detect acute cardiac syndromes in specified groups of patients using ECG

The present invention is, in one aspect, an imaging system having a detector that has multiple detector cells extending along a z-axis, the detector being configured to collect multiple slices of data; and a scalable data acquisition system configured to convert signals from the detector to digital form, the scalable data acquisition system having a plurality of converter boards each with a plurality of channels, the channels and detector cells having an interweaved coupling to reduce susceptibility to band artifact.

Scalable multislice imaging system

A scalable data acquisition system (SDAS) that may be used in connection with both single slice and multislice imaging systems is described. Generally, the SDAS in configured for use in a computed tomography system and converts the low level electrical current signal from the x-ray detector to digital values for image reconstruction, display and archive. The SDAS also includes an anti-alias filter for each cell prior to analog to digital conversion (ADC). More specifically, the analog current signals from the detector are supplied to the SDAS input channels via shielded ribbon or flex cables. The cables are connected to the SDAS at the SDAS backplane. The SDAS Converter boards are also plugged into the SDAS backplane. This interconnection provides several advantages. For example, the backplane enables ganging the detector cells on the outside edges of the fan beam. The backplane also allows a redistribution of the detector cells to appropriate converter boards. Signals from more than one slice are contained in the same flex cable, and each converter board only serves one slice since the reconfiguration of SDAS from one multi-slice configuration to another or to the single slice configuration requires only the removal or addition of converter boards. Also, the backplane enables a blending or weaving of SDAS channels and detector cells near the end channels of a converter board. Artifacts such as a band in the image are usually the result of common or uniform error source across one group of adjacent channels versus a neighboring group of channels. If all the channels on one converter board have a common error difference compared to a neighboring converter board, this type of image artifact is quite likely. By interweaving detector cell assignments versus converter card on the edges of the converter card, the susceptibility to a band artifact is reduced.

Scalable data acquisition system

A PET scanner contains a positron emission event qualifier which prevents noise from being misinterpreted as such an event. A radiation detector signal indicates the intensity and duration of sensed gamma radiation. A comparator produces an intermediate signal when the radiation detector signal exceeds a predetermined threshold. A delay line delays the intermediate signal by an interval of time and blocks any pulses in the intermediate signal which are shorter than this interval. Typical noise in the intermediate signal is shorter in duration than this interval of time.

Radiation event qualifier for positron emission tomography

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Dousman, WI, United States of America

Jonathan Alan Murray