Metavention, Inc.

Ethicon Endo-surgery, Inc.

Leland Stanford Junior University

Covidien LP

Prescient Surgical, Inc.

Medtronic Ireland Manufacturing Unlimited Company

Other

Tyco Healthcare Group LP

Precient Surgical, Inc.

Jonathan A Coe

Bobak Robert Azamian

Scott Bradley Vafai

Peter Michael Mueller

David Nichols Heard

John J Kappus

Tony Moua

Gary Lee Long

Kyle P Moore

Ryan C Artale

Andrew M Zwolinski

James Walden Voegele

Ronald J Podhajsky

Robert Perrin Gill

Richard F Schwemberger

Michael S Cropper

Thomas E Adams

Mark S Ortiz

Mark D Overmyer

David T Martin

Kevin D Felder

Eric W Thompson

David C Yates

Duane E Kerr

Michael J Stokes

Rudolph Henry Nobis

William H Nau, Jr

Omar J Vakharia

Scott Raymond Smith

Casey M Ladtkow

Christopher W Widenhouse

Anthony Ciro Vrba

David N Plescia

James G Hansen

Nicholas J Spinelli

Kelly Justin McCrystle

Jeremy Koehler

Insoo Suh

Swaminadhan Gnanashanmugam

Raymond A Sirianne

Mark Welton

Juan S Ezolino

John L Stammen

Edward Frederick Ruppel, Iii

Christopher T Rusin

Scott F Alexander

Kellie F Payne

James W Miser, Jr

Christine H Chen

Christine Hsin Yi Chen

Kevin McDermott

Mark Wilson Ian Webster

Joann M Stegeman

Mark D Overymyer

Michael David Perry

Eric Robert Reuland

Victor Kelvin Sun

William H Nau

Jeremy Christopher Koehler

Rossana Motta

Kevin Robert Hykes

Robert Jason Simms

David Martin

Juan S Ezolina

Christine Chen

Eric Thompson

According to some embodiments, a method of treating a subject having diabetes or symptoms associated with diabetes is provided. The method includes delivering a neuromodulation catheter within a vessel (e.g., hepatic artery) having surrounding nerves that innervate the liver (e.g., sympathetic nerves of the hepatic plexus). The method may also include modulating (e.g., disrupting, ablating, stimulating) the nerves by mechanical compression, energy delivery, or fluid delivery.

Neuromodulation for metabolic conditions or syndromes

According to various embodiments, systems, devices and methods for modulating targeted nerve fibers (e.g., hepatic neuromodulation) are provided. The systems may be configured to access tortuous anatomy of or adjacent hepatic vasculature. The systems may be configured to target nerves within a wall of (e.g., within adventitia surrounding a lumen of) an artery or other blood vessel, such as the common hepatic artery.

Modulation of targeted nerve fibers

A surgical access device and methods for facilitating access through an incision or wound to a surgical site in a patient's body comprising an inferior retention member, a superior retention member, and a pliable membrane therebetween. The pliable membrane includes a base layer, a permeable membrane attached to the base layer, and a fluid delivery region disposed between the layers. The fluid delivery region is fluidly coupled to a fluid source. The fluid is delivered to the surgical site via the permeable membrane. The inferior retention member provides for fluid removal from the surgical site. Methods are provided for use of the surgical access device to retract tissue and deliver fluid to the tissue from the pliable membrane.

Methods and apparatus for prevention of surgical site infection

A surgical access system facilitates access to a surgical site within a patient's body through an incision in the body. Surgical access systems can have at least one retention member and a fluid transportation member configured to deliver fluid to a surgical site or to remove fluid from a surgical site. In some embodiments, a surgical access device irrigates a surgical site to reduce surgical site infections and removes fluid from the surgical site to increase a physician's visibility into the surgical site.

Systems for the prevention of surgical site infections

A forceps includes an end effector assembly including first and second jaw members. One or both of the jaw members is movable relative to the other between a spaced-apart position and an approximated position for grasping tissue therebetween. One or both of the jaw members is configured to conduct energy between the jaw members and through tissue grasped therebetween to treat tissue. An insulative tubular member is movable relative to the end effector assembly between a retracted position, wherein the insulative tubular member is positioned proximally of the end effector assembly, and an extended position, wherein the insulative tubular member is disposed about the end effector assembly. A monopolar member is configured to apply energy to tissue to treat tissue when the insulative tubular member is disposed in the extended position.

Surgical forceps

A surgical access system that facilitates access to a surgical site through an incision in the patient's body includes a surgical retractor and a fluid delivery or fluid evacuation device. The fluid delivery or fluid evacuation device is coupled to the surgical retractor and is adapted to deliver fluid to the surgical site or evacuate fluid from the surgical site.

Methods and apparatus for reducing the risk of surgical site infections

Methods and devices are provided for performing various procedures using interchangeable end effectors. In general, the methods and devices allow a surgeon to remotely and selectively attach various interchangeable surgical end effectors to a shaft located within a patient's body, thus allowing the surgeon to perform various procedures without the need to remove the shaft from the patient's body. In an exemplary embodiment, multiple end effectors can be introduced into a body cavity. The end effectors can be disassociated or separate from one another such that they float within the body cavity. A distal end of a shaft can be positioned within the body cavity and it can be used to selectively engage one of the end effectors. In particular, the device can be configured to allow each end effector to be remotely attached and detached from the distal end of the shaft.

Detachable end effectors

Neuromodulation methods to alter glucose levels

Therapeutic denervation of nerves surrounding a hepatic vessel

A surgical access device for facilitating access through an incision to a surgical site in a patient's body has a pliable membrane which is configured to engage and expand the incision. The pliable membrane includes a base layer, a permeable membrane attached to the base layer, and a fluid channel disposed between the layers. The fluid channel is fluidly coupled to a fluid source. The fluid is delivered to the surgical site via the permeable membrane. The surgical access device may also have a locking mechanism for holding the device in a desired configuration.

Methods and devices for the prevention of incisional surgical site infections

A method is described for decreasing activity of at least one sympathetic nerve, nerve fiber or neuron innervating at least one blood vessel in the pulmonary vasculature of a patient to ameliorate pulmonary hypertension. In one embodiment, the method may involve advancing an intravascular treatment device to a target location in a target blood vessel within the pulmonary vasculature of the patient and using the treatment device to decrease activity of at least one sympathetic nerve, nerve fiber or neuron innervating the target blood vessel at or near the target location to ameliorate pulmonary hypertension.

Apparatus and methods for treating pulmonary hypertension

Growing community of inventors

Cincinnati, OH, United States of America

Jonathan A Coe