Tepha, Inc.

C. R. Bard, Inc.

Albany International Corporation

Jon I Montcrieff

David P Martin

Said Rizk

Dennis Connelly

Stephen N Eldridge

Scott Narkevicius

Frederick H Strickler, Jr

Christopher W Gelinas

Sarah B Borysenko

Simon F Williams

Dana Eagles

Fabio Felix

Robert Hansen

Jonas Karlsson

Joseph P Botelho

Sabri Mourad

Bruce Stowe

Jerry O'Connor

Dennis W Connelly

Implant

Methods to produce substantially closed cell foams with densities less than 0.75 g/cm, and more preferably less than 0.5 g/cm, without substantial loss of the polymer's weight average molecular weight, have been developed. The closed cells foams have an open cell content of generally less than 50%, and more preferably an open cell content of less than 20%, and the cells have a maximum diameter of less than 5 mm. The foam may include poly-4-hydroxybutyrate or a copolymer thereof. Preferably, the foam is derived by heating a foam polymer formula to a temperature above the melt temperature of the polymer to form a melt polymer system, adding a blowing agent to produce a foamable melt, extruding the foamable melt through a die to a lower pressure to cause foaming, cooling of the foam, and solidification of the foam. These foam structures can be used for fabrication of medical products.

Closed cell foams including poly-4-hydroxybutyrate and copolymers thereof

Biocompatible coatings and spin finishes that can be applied to polyhydroxyalkanoate (PHA) polymers, and medical devices made from PHA polymers, have been developed. The coatings impart good lubricity to PHA polymers, particularly to fibers and braids made from these materials, making the coatings ideal for use on medical devices such as PHA braided sutures. The spin finishes can be applied to PHA fibers to facilitate their manufacture, and also for their conversion to other products, including medical textiles. The spin finishes serve to protect multifilament fiber bundles, and keep them intact following extrusion, and also to impart lubricity to the fiber bundles and monofilament fibers so that they are not damaged in subsequent processing steps particularly in textile processing. The coating reduces tissue drag of, for example, braided sutures.

Coatings for the manufacture and application of polyhydroxyalkanoate medical devices

An industrial fabric, belt or sleeve and a method of making the fabric, belt or sleeve are disclosed. The industrial fabric, belt or sleeve is produced by spirally winding strips of polymeric material, such as an industrial strapping or ribbon material, and joining the adjoining sides of the strips of material using ultrasonic welding or laser welding techniques. The fabric, belt or sleeve may then be perforated using a suitable technique to make it permeable to air and/or water.

Industrial fabric including spirally wound material strips

An industrial fabric such as an endless belt or sleeve for use in the production of nonwovens, and a method of making thereof are disclosed. The industrial fabric is produced by spirally winding strips of polymeric material, such as an industrial strapping or ribbon material, and joining the adjoining sides of the strips of material using ultrasonic welding or laser welding techniques. The fabric may then be perforated using a suitable technique to make it permeable to air and/or water.

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Boston, MA, United States of America

Jon I Montcrieff