Janssen Pharmaceuticals, Inc.

Arsanis Biosciences Gmbh

X4 Pharmaceuticals (austria) Gmbh

Instytut Immunologii I Terapii Doswiadczalnej Pan

Instytut Biologii Medycznej Polskiej Akademii Nauk

Instytut Immunologii I Terapii Doswiadczalnej Polskiej Akademii Nauk

Jolanta Lukasiewicz

Eszter Nagy

Gábor Nagy

Valéria Szijárto

Irina Mirkina

Adriana Badarau

Gerhild Zauner

Luis Guachalla

Zoltán Magyarics

Zóltan Magyarics

Luis Gauchalla

Czeslaw Lugowski

Tomasz Niedziela

Zehra Visram

Anna Swierzko

Maciej Cedzynski

Anna Maciejewska

Wojciech Jachymek

Gäbor Nagy

The subject relates to an isolated antibody that specifically binds to O25b antigen of multi drug resistant (MDR)strains, its medical and diagnostic use, method of producing the antibody, including an isolated nucleotide sequence, plasmids and host cells as used in the production of the antibody; and further an isolated epitope recognized the specific antibody.

MDRimmunogen

The invention provides for an isolated antibody that specifically recognizes a galactan-III epitope of the lipopolysaccharide (LPS) O-antigen structure of, which epitope is incorporated in galactan-III repeating units, wherein the galactan-III repeating unit is a branched galactose homopolymer of Formula (I). The invention further provides for a pharmaceutical or diagnostic preparation comprising said antibody, and a method of producing said antibody. 

Antibodies targeting a galactan-based O-antigen of K. pneumoniae

MDRspecific antibody

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The invention relates to bacterial lipopolysaccharide and its components, especially native and chemically modified polysaccharides isolated fromlipopolysaccharides, as well as conjugates of these polysaccharides with carriers and methods for their preparation and methods to use of these substances as ligands for human ficolin-3.

Polysaccharide and derivatives thereof, showing affinity to ficolin-3, method of preparation and use

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Wroclaw, Poland

Jolanta Lukasiewicz