Emory University

Altiris Therapeutics, Inc.

John Wiseman

Michael G Natchus

Lawrence J Wilson

Dennis C Liotta

Florence Fevrier Wagner

Michael P Clark

Yesim Altas Tahirovic

Mark A Lockwood

Brandon C Doroh

Jason W Skudlarek

Tricia L Johnson

Lawrence Wilson

The disclosure relates to chemokine CXCR4 receptor modulators and uses related thereto. In certain embodiments, the disclosure relates to pharmaceutical compositions comprising compounds disclosed herein or pharmaceutically acceptable salts or prodrugs thereof. In certain embodiments, the compositions disclosed herein are used for managing CXCR4 related conditions, typically prevention or treatment of viral infections such as HIV or for managing cancer.

Chemokine CXCR4 receptor modulators and uses related thereto

The invention provides compounds of Formula (I) and pharmaceutically acceptable salts, solvates, tautomers, stereoisomers, and/or esters thereof. These compounds, and pharmaceutical composition comprising such compounds are useful treating or preventing HIV infections, and in treating proliferative disorders such as inhibiting the metastasis of various cancers.

Chemokine receptor modulators

Chemokine CXCR4 receptor modulators and used related thereto

Growing community of inventors

Atlanta, GA, United States of America

John Wiseman