Shionogi Company Limited

Purdue Pharma L.p.

Euro-celtique S.a.

John William Frank Whitehead

Jiangchao Yao

R Richard Goehring

Yoshiyuki Taoda

Naoki Tsuno

Bin Shao

Kouki Fuchino

Donald Kyle

Qun Sun

Laykea Tafesse

Xiaoming Zhou

Akira Matsumura

Parviz Gharagozloo

Ji Yang

Khondaker Islam

The invention relates to Substituted-Quinoxaline-Type Piperidine Compounds, compositions comprising an effective amount of a Substituted-Quinoxaline-Type Piperidine Compound and methods to treat or prevent a condition, such as pain, comprising administering to an animal in need thereof an effective amount of a Substituted-Quinoxaline-Type Piperidine Compound.

Substituted-quinoxaline-type piperidine compounds and the uses thereof

A compound of formula(wherein A, R, R, R, m and n are disclosed herein) or a pharmaceutically acceptable salt thereof (a 'Piperazine Compound'); pharmaceutical compositions comprising a Piperazine Compound; and methods for treating pain, urinary incontinence (UI), an addictive disorder, Parkinson's disease, parkinsonism, anxiety, epilepsy, stroke, a seizure, a pruritic condition, psychosis, a cognitive disorder, a memory deficit, restricted brain function, Huntington's chorea, amyotrophic lateral sclerosis (ALS), dementia, retinopathy, a muscle spasm, a migraine, vomiting, dyskinesia and depression in an animal comprising administering to an animal in need thereof an effective amount of a Piperazine Compound are disclosed.

Therapeutic agents useful for treating pain

Growing community of inventors

Newtown, PA, United States of America

John William Frank Whitehead