Alcon Laboratories, Inc.

Alcon Universal Ltd.

Alcon, Inc.

Alcon Manufacturing, Ltd.

John W Sheets, Jr

Mutlu Karakelle

Stephen J Van Noy

Anilbhai S Patel

Albert R Leboeuf

Albert R LeBoeuf

John M Yanni

John Alfred Campin

George H Pettit

Gustav Graff

Kwan Y Chan

Kevin Lewellen

A method for optimizing a prescription for laser-ablation corneal treatment or ophthalmic implant includes the steps of receiving a measured correction prescription for a current patient having a classification element associated therewith, the prescription having been measured using wavefront determination. A database of treatment outcomes on a plurality of previously treated patients is accessed, each treated patient outcome having associated therewith at least one classification element and comprising a preoperative wavefront-determined correction prescription and a postoperative visual profile. From the treatment outcomes in the database is calculated an average difference between the preoperative prescription and the postoperative profile for at least some of the previously treated patients having a classification element in common with the current patient. Finally the current patient correction prescription is adjusted commensurate with the calculated average difference to form an optimized prescription.

Adaptive wavefront modulation system and method for ophthalmic surgery

Hydrophilic coatings for implantable ophthalmic lenses are disclosed. The coatings, which are applied to the edge surface of the ophthalmic lens, comprise a hydrophobic (meth)acrylic polymer and a hydrophilic polymer. When hydrated, the coatings reduce or eliminate edge glare.

Coating compositions and methods for reducing edge glare in implantable ophthalmic lenses

A method for determining the propensity of an intraocular lens material to prevent posterior capsule opacification is disclosed. The method involves contacting a sample of an IOL material having the shape of an IOL optic with collagen to form a contact area, incubating the sample in a liquid composition comprising lens epithelial cells, determining whether lens epithelial cells grow on the collagen in the contact area.

Lens epithelial cell growth assay for intraocular lens materials

Bicomposite intraocular lenses having an anterior surface material different from a posterior surface material are disclosed. The posterior surface material reduces the risk of posterior capsule opacification.

Bicomposite intraocular lens and method for its preparation

Intraocular lens coating compositions for reducing the risk of posterior capsule opacification are disclosed. The coating materials, which differ from the substrate material, consist essentially of at least two aryl acrylic hydrophobic monomers of the formula

Intraocular lens coating compositions

A method for polishing articles comprising soft acrylic materials is disclosed. The method includes a cryogenic polishing step and a cleaning step. In the polishing step, a receptacle is charged with polishing beads of various sizes, sodium bicarbonate, a swelling agent and the articles to be polished, for a period of time and at a rotation speed sufficient to remove surface irregularities. Following the polishing step, a receptacle is charged with (a) a cleaning slurry comprising cleaning beads of various sizes and (i) sodium hydroxide and water or (ii) alumina, a surfactant and a solvent and (b) the articles to be cleaned, for a period of time and at a rotation speed sufficient to clean the surface of the polished articles. Agitation is preferably accomplished by a tumbling machine.

Cryogenic polishing method for soft acrylic articles

Improved glaucoma filtration device materials comprise at least one monomer having the formula: ##STR1## wherein: X is H or CH.sub.3 ;

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Fort Worth, TX, United States of America

John W Sheets, Jr