Pacesetter, Inc.

Siemens-pacesetter, Inc.

Siemens Elema Ab

John W Poore

Gene A Bornzin

Zoltan Somogyi

Brian M Mann

Xiaoyi Min

Joseph J Florio

Yelena Nabutovsky

Didier Theret

Douglas T Kurschinski

Taraneh Ghaffari Farazi

Roy B Medlin

Richard Samade

Gabriel A Mouchawar

Jeffery D Snell

Eric Steven Fain

Sheldon Williams

Edward Karst

Richard P Williamson

Annapurna Karicherla

Harold C Schloss

Mark W Kroll

Euljoon Park

Peter Boileau

Laurence S Sloman

Jason A Sholder

Gary R Dulak

Martin Cholette

Weiqun Yang

Naixiong Jiang

Nirav Dalal

Eric Falkenberg

Ali Dianaty

Prashant Dinesh

Kerry A Bradley

Kelly Hobart McClure

Paul A Levine

Kyungmoo Ryu

Yougandh Chitre

Steve Koh

Keith Victorine

Buehl E Truex

Anders Bjorling

Rodney J Hawkins

Balakrishnan Shankar

Stuart W Buchanan

Dion F Davis

Kenneth R McNeil, Ii

Nalin S Perera

Hans T Thornander

Jonathan A Kleks

Raymond J Wilson

Elaine Karaelias

Enzo Silipo

Adam Klonecke

Malcolm Clarke

David C Amundson

James R Thacker

Gene A Borzin

A renal denervation feedback method is described that performs a baseline measurement of renal nerve plexus electrical activity at a renal vessel; denervates at least some tissue proximate the renal vessel after performing the baseline measurement; performs a post-denervation measurement of renal nerve plexus electrical activity at the renal vessel, after the denervating; and assesses denervation of the renal vessel based on a comparison of the baseline measurement and the post-denervation measurement of renal nerve plexus electrical activity at the renal vessel.

System and method for performing renal denervation verification

A leadless intra-cardiac medical device is configured to be implanted entirely within a heart of a patient. The device includes an intra-cardiac extension and a housing. The intra-cardiac extension includes a loop body having at least one loop segment retaining at least one coil group that is configured to one or both of receive and transmit radio frequency (RF) energy, wherein the loop body is configured to extend into a first chamber of the heart. The housing is in electrical communication within the loop body, and includes a transceiver, control logic and an energy source. The housing is configured to be securely attached to an interior wall portion of a second chamber of the heart, wherein the transceiver is configured to communicate with an external device through the RF energy.

Leadless intra-cardiac medical device with built-in telemetry system

A leadless intra-cardiac medical device (LIMD) includes an electrode assembly configured to be anchored within a first wall portion of a first chamber of a heart. The electrode assembly includes an electrode main body having a first securing helix, an electrode wire segment extending from the body, and a first segment-terminating contact positioned on the electrode wire segment. The device further includes a housing assembly configured to be anchored within a second wall portion of a second chamber of the heart. The housing assembly includes a body having a second securing helix, a housing wire segment extending from the body, and a second segment-terminating contact positioned on the housing wire segment. The device also includes a connector block that electrically connects the electrode wire segment to the housing wire segment by retaining the first and second segment-terminating contacts.

Multi-piece dual-chamber leadless intra-cardiac medical device and method of implanting same

A method of implanting a leadless intra-cardiac medical device. An introducer assembly is introduced into one of an inferior vena cava or a superior vena cava of a heart and maneuvered into a first chamber of the heart. A housing is pushed out of a sheath of the introducer toward a first implant location within the first chamber, and the housing is anchored to the first implant location. The sheath is moved away from the anchored housing, and an electrode is urged to a distal end of the sheath due to the pushing, anchoring, and moving. The sheath is maneuvered to a second chamber of the heart, and the electrode is forced into a second implant location with the second chamber. The electrode is anchored to the second implant location. The sheath is moved away from the electrode after the anchoring, and the sheath is removed from the heart.

Method of implanting a unitary dual-chamber leadless intra-cardiac medical device

A distributed leadless implantable system and method are provided that comprise a leadless implantable medical device (LIMD). The LIMD comprises a housing having a proximal end configured to engage local tissue of interest in a local chamber, cardiac sensing circuitry to sense cardiac signals; and a controller configured to analyze the cardiac signals and, based thereon, to produce a near field (NF) event marker indicative of a local event of interest (EOI) occurring in the local chamber. The system and method further comprise a subcutaneous implantable medical device (SIMD). The SIMD comprises cardiac sensing circuitry to sense cardiac signals, a controller configured to identify a candidate EOI from the cardiac signals, and pulse sensing circuitry to detect the NF event marker from the LIMD. The SIMD controller is configured to declare the candidate EOI as a valid EOI or an invalid EOI based on the NF event marker.

Method and system for tracking events of interest between leadless and subcutaneous implantable cardioverter devices

Medical device including a lift tool having a distal end configured to removably engage an anatomic layer. The lift tool includes a shaft lumen that extends longitudinally through the lift tool and through the distal end. The shaft lumen is configured to receive an elongated insert device that is movable through the shaft lumen and through the distal end. The medical device also includes a locking mechanism that is coupled to the lift tool. The locking mechanism includes a locking member that is selectively movable with respect to the insert device between a released position and an engaged position. The locking member engages the insert device when in the engaged position to hold the insert device at a fixed position with respect to the lift tool and permits the insert device to move through the shaft lumen when in the released position.

Medical device for accessing space along an interior surface of an anatomic layer

A bioelectric battery may be used to power implantable devices. The bioelectric battery may have an anode electrode and a cathode electrode separated by an insulating member comprising a tube having a first end and a second end, wherein said anode is inserted into said first end of said tube and said cathode surrounds said tube such that the tube provides a support for the cathode electrode. The bioelectric battery may also have a membrane surrounding the cathode to reduce tissue encapsulation. Alternatively, an anode electrode, a cathode electrode surrounding the cathode electrode, a permeable membrane surrounding the cathode electrode. An electrolyte is disposed within the permeable membrane and a mesh surrounds the permeable membrane. In an alternative embodiment, a pacemaker housing acts as a cathode electrode for a bioelectric battery and an anode electrode is attached to the housing with an insulative adhesive.

Bioelectric battery for implantable device applications

A leadless intra-cardiac medical device senses cardiac activity from multiple chambers and applies cardiac stimulation to at least one cardiac chamber and/or generates a cardiac diagnostic indication. The leadless device may be implanted in a local cardiac chamber (e.g., the right ventricle) and detect near-field signals from that chamber as well as far-field signals from an adjacent chamber (e.g., the right atrium).

Leadless intra-cardiac medical device with dual chamber sensing through electrical and/or mechanical sensing

A leadless implantable medical device (LIMD) includes a housing formed from a battery and an end cap. A proximal end of the end cap forms an LIMD proximal end and a distal end of the battery case forms an LIMD distal end. A non-conductive coupler mechanically secures a terminal end of the battery case to a mating end of the end cap, while maintaining the battery case and end cap electrically separated. A first electrode projects from the proximal end of the end cap. An intra-cardiac (IC) device extension projects from the distal end of the battery case. The extension includes a second electrode that is electrically connected to the battery case. The second electrode is located remote from the LIMD distal end. An electronics module is located within an internal cavity of the end cap and communicates with the first and second electrodes.

Leadless intra-cardiac medical device with reduced number of feed-thrus

An implantable physiologic sensor assembly is configured to be implanted within a patient. The assembly includes a module that houses an internal operative chamber, and a flexible pressure-detecting member connected to the module. The module and the pressure-detecting member are separated before implantation into the patient. At least a first end of the pressure-detecting member is configured to be inserted into an artery of the patient and a second end of the pressure-detecting member is connected to the module. The module is configured to be subcutaneously positioned within the patient.

System and method for implanting a physiologic sensor assembly

Disclosed herein is an implantable medical device including an antimicrobial layer. The antimicrobial layer may include a first distinct size of silver nanoparticles, a second distinct size of silver nanoparticles, and a third distinct size of silver nanoparticles. The antimicrobial layer extends over a surface of the implantable medical device, and, in some instances, the surface of the implantable medical device may serve as a substrate on which the antimicrobial layer is deposited.

Silver nanoparticle antimicrobial coating for long-term and short-term infection resistance

A high voltage resonant step-up convertor converts a lower voltage signal to a higher voltage signal. The converter may be used, for example, to supply power via electromagnetic coupling to an implantable medical device. In some embodiments, a power converter comprises a driver circuit and a resonant circuit. The resonant circuit generates a high voltage output signal at a selected frequency. The driver circuit is controlled by a low voltage signal and periodically generates a higher frequency signal (e.g., approximately twice the selected frequency) to drive the resonant circuit. In some embodiments, the driver circuit comprises another resonant circuit and a switching circuit. The switching circuit periodically pumps current to the other resonant circuit and isolates the two resonant circuits. The other resonant circuit periodically pumps current to the output resonant circuit.

Power converter with first and second resonant circuits

Growing community of inventors

South Pasadena, CA, United States of America

John W Poore