E.i. Dupont De Nemours and Company

John W Grant

John R Wells

Joseph J Kirkland

Wallace W Yau

Continuous, noncentrifugal, unit gravity, sedimentation apparatus for separating blood into an erythrocyte-enriched plasma fraction and a leukocyte/platelet-enriched plasma fraction.

Apparatus for continuous separation of leukocyte/platelet-enriched

Continuous, noncentrifugal, unit gravity, sedimentation process and apparatus for carrying out the process, for separating blood into an erythrocyte-enriched plasma fraction and a leukocyte/platelet-enriched plasma fraction.

Process for continuous separation of leukocyte/platelet-enriched

A long, thin annular belt-like channel is designed for use in sedimentation field flow fractionation. This channel, which may be contained in the rotor of a centrifuge, has a generally rectangular cross-section. It has an inlet positioned to introduce particulates (includes particles and/or macromolecules) approximately at the radial distance from the outer wall that is the equilibrium distance resulting from the average force field exerted on each particulate by the centrifugal force field and by the opposing normal diffusion forces due to Brownian motion. An outlet for the channel is similarly located. A modified design tapers the inlet and outlet.

Apparatus for field flow fractionation

A long, thin annular belt-like channel is designed for use in sedimentation field flow fractionation. This channel, which may be the rotor of a centrifuge, is designed to maintain its thickness dimension constant by forming the radially inner wall with a radial thickness that is about balanced by the centrifugal pressure of fluid in the flow channel.

Rotor for sedimentation field flow fractionation

A long, thin annular belt-like channel is designed for use in sedimentation field flow fractionation. This channel, which is the rotor of a centrifuge, is designed to maintain its thickness dimension constant and yet facilitate its manufacture and cleaning by forming the rotor of a double mating ring in which the inner ring is split. This permits the inner ring to conform to the outer load carrying ring.

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Chadds Ford, PA, United States of America

John W Grant