Neurosystec Corporation

Other

Advanced Therapeutics and Diagnostics, Lc

John V Schloss

Thomas Jay Lobl

Jacob E Pananen

Anna Imola Nagy

Stephen J McCormack

Morris D Faiman

Jang-Yen Wu

Drug solutions (or other combinations of vehicle with entrained drug) are prepared by removing drug from one or more masses of a solid form of the drug. The solid form of the drug may be sparingly soluble or insoluble in water. Examples of devices for holding solid drug and facilitating delivery of such drug to targeted regions are also described.

Flow-induced delivery from a drug mass

Implantable drug delivery systems target delivery of small volumes of drugs to specific tissues. In some cases, a drug delivery system includes an implantable osmotic pump connected to a drug-containing housing, with that housing connected to a needle, cochlear implant or other type of component for ultimate delivery to the target tissue. In some implementations, a subcutaneous port receives a fluid from an external pump. The port is connected to a needle or other component for delivery of one or more drugs to the target tissue. Both solid and liquid drug formulations can be used. In embodiments using solid drugs, a separate drug vehicle (such as saline) can be used to dissolve a portion of the solid drug, with the drug-loaded vehicle then delivered to the target tissue.

Apparatus and method for delivery of therapeutic and other types of agents

A method is provided for the preparation of compounds of the formula (R)(R)NC(&#x2550;X)S(O)Ror (R)(R)NC(&#x2550;X)OS(O)R, wherein R, Rand R, X and n have any of the meanings defined in the specification. A method is also provided for the detection and quantitation of compounds of the formula (R)(R)NC(&#x2550;X)OS(O)R. A method to link a therapeutic agent to a compound that is conjugated to glutathione is also provided for the purpose of improving the therapeutic properties of the therapeutic agent. Novel compounds, intermediates, pharmaceutical compositions and methods of use are also provided.

Therapeutic compositions

Method for treatment of glutamate related disorders

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Saugus, CA, United States of America

John V Schloss