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Curadel Surgical Innovations, Inc.

John V Frangioni

Wolfgang Maison

The present invention relates to zwitterionic metal chelators and their use as imaging, diagnostic, chemical processing, and treatment agents. These zwitterionic metal chelators have desirable properties that maximize solubility in aqueous environments, minimize non-specific interactions, and retain the ability to target thus resulting in an improved performance in a variety of medical, agricultural, and chemical processes. In in vivo and medical applications, zwitterionic metal chelators improve the signal-to-background ratio and therapeutic window as compared to other metal chelators while retaining high stability.

Zwitterionic metal chelators

Apparatus and method for forming an electrophoretic gel having a polymer. The apparatus has at least two sealed compartments, with separate inner volumes. The inner volumes are separated from each other by at least one burstable seal. In one inner volume is a monomer which can be polymerized to form the polymer. In other inner volume is a catalyst. Bursting of the burstable seal allows the monomer and catalyst to contact each other and, in conjuction with any other necessary components held within the apparatus, to form a liquid medium in the apparatus which will then form the electrophoretic gel under suitable conditions.

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Weston, MA, United States of America

John V Frangioni