Abbvie Inc.

Abbott Laboratories Corporation

Calico Life Sciences LLC

Abbvie Bahamas Limited

Abbvie Ireland Unlimited Company

John T Randolph

Allan C Krueger

David A DeGoey

Charles A Flentge

Rolf Wagner

Douglas K Hutchinson

Pamela L Donner

Dachun Liu

Todd Warren Rockway

David A Betebenner

Warren M Kati

John K Pratt

Clarence J Maring

Christopher E Motter

Yi Gao

Sachin V Patel

Charles W Hutchins

Larry L Klein

Michael D Tufano

Lissa T Nelson

Kevin R Woller

Peggy Huang

Kenton L Longenecker

Tammie K Jinkerson

Mark A Matulenko

Ryan G Keddy

Dale J Kempf

Kent D Stewart

Ming Clinton Yeung

Kathy A Sarris

Seble H Wagaw

Wenke Li

Mary E Bellizzi

Daniel D Caspi

David A Degoey

William A Carroll

Geoff G Z Zhang

Shuang Chen

Hui-Ju J Chen

Xiaochun Lou

Yaya Liu

Jean C Califano

Anthony Ralph Haight

Michael R Schrimpf

David M Barnes

Geoff G Zhang

David J Grampovnik

Darold L Madigan

William J Flosi

Qingwei I Zhang

Brian J Kotecki

Fortuna Haviv

Daryl Richard Sauer

Eric A Voight

Christopher R Dalton

Jonathan Greer

Nicholas A Mort

Christopher C Marvin

Todd N Soltwedel

Chen Zhao

Milan Bruncko

Rodger F Henry

Yi-Yin Ku

Keith F McDaniel

Tao Li

Tongmei Li

Minghua Sun

Thomas B Borchardt

Pramila A Bhatia

Tami J Pilot-Matias

Richard J Perner

Brian S Brown

M Robert Leanna

Russell Drew Cink

Brian E Green

Vincent S Stoll

Zhiren Xia

Mira Hinman

Teresa A Rosenberg

Jean-Christophe C Califano

Richard D Bishop

Bradley D Gates

Preethi Krishnan

John E Hengeveld

John Hartung

Daniel P Larson

Todd D Bosse

Michael J Dart

Jennifer M Frost

Adrian Hobson

Xiu Chun Wang

Lei Shi

Marina Pliushchev

Yunsong Tong

Howard Robin Heyman

Xiangdong Xu

Anurupa Shrestha

Su Yu

Charles J Nichols

Michael McPherson

Provided herein are compounds, compositions, and methods useful for modulating the integrated stress response (ISR) and for treating related diseases, disorders and conditions.

Prodrug modulators of the integrated stress pathway

Provided herein are glucocorticoid receptor agonist immunoconjugates, glucocorticoid receptor agonists, and methods of using the same, e.g., to treat autoimmune or inflammatory diseases.

Glucocorticoid receptor agonist and immunoconjugates thereof

The present invention features compounds effective in inhibiting active against Hepatitis C virus ('HCV') polymerase. The invention also features processes of making such compounds, compositions comprising such compounds, and methods of using such compounds to treat HCV infection.

Anti-viral compounds

Compounds effective in inhibiting replication of Hepatitis C virus ('HCV') are described. This invention also relates to processes of making such compounds, compositions comprising such compounds, and methods of using such compounds to treat HCV infection.

This invention relates to: (a) compounds and salts thereof that, inter alia, inhibit HCV; (b) intermediates useful for the preparation of such compounds and salts; (c) compositions comprising such compounds and salts; (d) methods for preparing such intermediates, compounds, salts, and compositions; (e) methods of use of such compounds, salts, and compositions; and (f) kits comprising such compounds, salts, and compositions.

Antiviral compounds and uses thereof

This invention relates to: (a) compounds and salts thereof that, inter alia, treat pain; (b) intermediates useful for the preparation of such compounds and salts; (c) compositions comprising such compounds and salts; (d) methods for preparing such intermediates, compounds, salts, and compositions; (e) methods of use of such compounds, salts, and compositions; and (f) kits comprising such compounds, salts, and compositions.

Agents for treating pain and uses thereof

Anti-infective agents and uses thereof

Growing community of inventors

Libertyville, IL, United States of America

John T Randolph