Transmedics, Inc.

Juniper Networks, Inc.

Transmedic, Inc.

John Sullivan

Waleed H Hassanein

Richard Bringham

Tamer I Khayal

Mark Anderson

Scott W Newell

Stanley Kyi

Robert Havener

Robert Fishman

Ihab Abdel Fattah

Anas Abdelazim

Greg Ritchie

Doug Harriott

Matthew De Remer

Paul Murray

Michael Van Driel

Ron Taylor

Ahmed Elbetanony

Jeff Barnes

Tom Bishop

Vincent Lambert, Ii

Thomas H Bishop

Ronald Taylor

Vincent Lambert Ii

Methods and systems of maintaining, evaluating, and providing therapy to a lung ex vivo. The methods and systems involve positioning the lung in an ex vivo perfusion circuit; circulating a perfusion fluid through the lung, the fluid entering the lung through a pulmonary artery interface and leaving the lung through a left atrial interface; and ventilating the lung by flowing a ventilation gas through a tracheal interface. Maintaining the lung for extended periods involves causing the lung to rebreath a captive volume of air, and reaching an equilibrium state between the perfusion fluid and the ventilation gas. Evaluating the gas exchange capability of the lung involves deoxygenating the perfusion fluid and measuring a time taken to reoxygenate the perfusion fluid by ventilating the lung with an oxygenation gas.

Systems and methods for ex vivo lung care

The invention provides, in various embodiments, devices and methods relating to ex-vivo organ care. In certain embodiments, the invention relates to aortic cannulas for use in perfusion systems to return perfusate to the heart or delivering perfusate from the heart while the organ is sustained ex vivo at physiologic or near-physiologic conditions.

Aortic cannula for ex vivo organ care system

The invention generally relates to systems, methods, and devices for ex vivo organ care. More particularly, in various embodiments, the invention relates to caring for a liver ex vivo at physiologic or near-physiologic conditions.

Ex vivo organ care system

The disclosure generally relates to a system for perfusing an ex-vivo liver including a pump configured to pump a perfusion fluid through a perfusion circuit, the pump in fluid communication with a hepatic artery interface and a portal vein interface; an oxygenator; a heater; an inferior vena cava interface in fluid communication with an inferior vena cava of the ex-vivo liver; and a reservoir configured to receive the perfusion fluid from the inferior vena cava of the ex-vivo liver and store a volume of fluid.

A network device is described that concurrently executing more than one instance of an operating system on a single processor. Each of the instances of the operating system executes completely independent of the other instances. In this way, disparate instances may exist for the same operating system or for different operating systems. The techniques allow the processor to concurrently execute, for example, an instance of the operating system may emulate a routing engine and an instance of the operating system may emulate an interface controller. A hyper scheduler performs context switches between the operating systems to enable the processor to concurrently execute the instances of the operating system. The techniques may provide a low cost alternative to employing multiple processors within a network device, such as a router, to execute multiple independent operating systems.

Router having routing engine software instance and interaface controller software instance on a single processor

Growing community of inventors

Groton, MA, United States of America

John Sullivan