Hewlett-packard Development Company, L.p.

Other

Hewlett-packard Company

Oregon State University

John Stephen Dunfield

Steven J Simske

Winthrop D Childers

Adam L Ghozeil

Paul H McClelland

David Alvin Tyvoll

Douglas A Sexton

Paul Crivelli

Donald J Milligan

James W Ayres

Grant Pease

Daryl E Anderson

Makarand P Gore

Timothy L Weber

Daniel Robert Blakley

Craig Olbrich

Paul S Everest

Enrique C Abreu

Jose M Gonzalez

Roberto Rivera

James W Ayers

Linda Williams Dunfield

Wojtek Kolodziej

Frank Chaplen

Rosalyn H Upson

Ronni J Yenchik

Carlos A Martinez

Malgorzala M Sturgill

Paul H Mcclelland

The present invention is drawn to methods of preparing a bioactive agent-containing emulsion for delivery to a biological system. This method can comprise the step of jetting a bioactive agent and a first fluid medium from a fluid-jet pen into a second fluid medium to form a bioactive agent-containing emulsion, wherein the second fluid comprises a continuous phase of the emulsion. Alternatively, a method of preparing a bioactive agent-containing liposome can comprise jetting a lipid-containing composition and a bioactive agent from a fluid-jet pen into a medium to form a bioactive agent-containing liposome carried by the medium. The present invention is also drawn to fluid-jet pens and systems configured for making liposome- and emulsion-containing biological agents.

Fluid-jet pens configured for making modulated release bioactive agents

A method for enhancing security printing includes generating data for a region of interest (), where the data includes information for at least one of locating or analyzing the region of interest () using a secure registry (). The method further includes encrypting a deterrent () with the data, and printing the deterrent () and the region of interest () on an object ().

Security printing analysis system and method for enhancing security printing

Embodiments of an ophthalmic apparatus are disclosed for administering fluids to the eye. In one disclosed embodiment, the ophthalmic apparatus includes an eye-positioning device for assisting a subject in positioning an eye in a desired position for administering the fluid and a fluid applicator for dispensing the fluid into the eye when the eye is in the desired position.

Ophthalmic apparatus and method for administering agents to the eye

A method for making a patient monitor includes providing an electronic device operatively connected to the monitor. The device is configured to measure predetermined signals from a user and to generate therefrom a substantially unique signature specific to the user. The method further includes storing the signature in the electronic device. The electronic device is adapted to compare newly acquired signatures to the substantially unique signature, and to recognize at least one difference from the substantially unique signature. Recognition of a difference in the signatures signifies a new user, whereupon the electronic device acquires new predetermined signals and generates therefrom a new substantially unique signature specific to the new user.

Method of making a patient monitor

A microfluidic device for analysis of a sample. The microfluidic device includes a substrate portion that at least partially defines a chamber for receiving the sample. The substrate portion includes a substrate having a surface. The substrate portion also includes a plurality of thin-film layers formed on the substrate adjacent the surface. The thin-film layers form a plurality of electronic devices. Each of at least two of the electronic devices is formed by a different set of the thin-film layers.

Microfluidic device with thin-film electronic devices

A microtray for handling biosubstances comprises a fluid holding structure and a fluid ejection structure. The fluid holding structure includes an array of wells with each well configured to contain at least one biosubstance. The fluid ejection structure is in communication with the fluid holding structure and configured to dispense the at least one biosubstance onto a target media.

Microtray for handling biosubstances

A method of making microcapsules including activating a fluid ejector at a frequency greater than 10 kilohertz where each activation of the fluid ejector generates essentially a drop, and the fluid ejector is fluidically coupled to a first fluid including a core component. The method further includes ejecting the drop of the first fluid into a second fluid, the drop having a volume. In addition, the method includes generating a microcapsule, that includes the core component, in the second fluid for each drop of the first fluid ejected.

Method of making microcapsules utilizing a fluid ejector

A microfluidic device for analysis of a sample. The microfluidic device includes a substrate portion that at least partially defines a chamber for receiving the sample. The substrate portion includes a substrate having a surface. The substrate portion also includes a plurality of thin-film layers formed on the substrate adjacent the surface. The thin-film layers form a plurality of electronic devices. Each of at least two of the electronic devices is formed by a different set of the thin-film layers. The at least two electronic devices may include 1) a temperature control device for controlling the temperature of fluid in the chamber, and 2) an other electronic device configured to sense or modify a property of fluid in the chamber.

A culture device for cellular media including a biomedia growth chamber defining a closed environment and an electronically controllable jetting device in communication with a source of material supporting biological function. The jetting device emits the material into the biomedia growth chamber.

Cell culture device

A method and device for delivering a quantity of at least one material to a selected single cell in a manner that permits impingement of material with the cell. The material travels at a suitable trajectory and velocity and is ejected from an electronically controllable fluid device.

Method and device for targeted delivery of materials to selected single cells

The present invention discloses a method and apparatus for producing high surface area material films and membranes on substrates. In one application, patterns of spikes or bristles are produced on wafers and transferred to films, such as conductive polymer or metal films, by using repetitive and inexpensive processes, such as electroplating and embossing. Such a technique provides low cost, high surface area materials and allows reuse of expensive patterned silicon. Membranes with high surface area are extremely valuable in fuel cells since the power density is generally proportional to the surface area and the patterns may be used to cast inexpensive fuel cell electrodes.

Method and apparatus for forming high surface area material films and membranes

A power switch control unit for controlling the operation of a controlled electric device connected to the unit includes a housing having a timing mechanism therein; a power cord having a plug on one end thereof, for connection to a power supply, and having the housing on the other end thereof, for supplying electrical power to the unit and to a connected-electric device controlled by the power switch control unit, and a receptacle for receiving a power cord from an electric device to be controlled by the power switch control unit; control buttons, including: an on/off button for connecting a controlled electric device to the power supply; a timer activation button for activating the timing mechanism, wherein, when the timing mechanism is activated, it connects a controlled electric device to the power supply for a predetermined amount of time in a timed cycle, and then disconnects the connected-electric device from the power supply; and a clear timer button for terminating the predetermined amount of time, and a display for displaying time remaining in the predetermined period of time.

Timed switch control for electric devices

A fluid ejector head, includes a fluid ejector body adapted to be inserted into an opening of an enclosing medium having an interior surface, and at least one nozzle disposed on the fluid ejector body. The fluid ejector head further includes, a fluid ejector actuator in fluid communication with the at least one nozzle, wherein activation of the fluid ejector actuator ejects a fluid through the at least one nozzle at controlled locations onto the interior surface of the enclosing medium.

Fluid ejector apparatus and methods

A portable sensor device for obtaining physiological information, including cardiopulmonary information, from a human or animal subject. The device includes a housing having a lumen and a respiratory port in fluid communication with the lumen. The lumen can be divided into plural airflow tubes. Spirometric data can be integrated with non-spirometric cardiopulmonary data collected by the device. Additionally, the sensor device can be operably coupled to a bioactive composition delivery device. Methods for using the sensor device and methods for making the sensor device also are disclosed.

Multi-function sensor device and methods for its use

A low temperature process for silicon-based field emitter tip sharpening. A rough silicon-based field emitter tip is exposed to xenon difluoride gas in a process chamber to carry out low-temperature, isotropic etching of the rough silicon-based field emitter tip to produce a final, sharpened field emitter tip.

Growing community of inventors

Corvallis, OR, United States of America

John Stephen Dunfield