National Research Development Corporation

University of Southampton

The Boots Company Plc

Hvivo Services Limited

Retroscreen Ltd.

John Sidney Oxford

Geoffrey C Schild

Robert Lambkin-Williams

James S Robertson

Thomas Wilkinson

David A Tyrrell

The present invention provides screening methods which may be regarded as in vitro or ex vivo methods of interrogating the immune system to understand what viral antigens are 'seen' and responded to by T cells of the immune systems during viral infection. The screening methods further link in vitro or ex vivo responses to progression of infection in subjects.

Vaccine&#x2014;screening method

2,4-dichlorobenzyl alcohol and amylmetacresol against HIV infection

The present invention relates to the production of vaccines having improved safety, particularly to a process therefor which allows even an AIDS vaccine to be manufactured, comprising in order, the steps of:

Vaccines and methods for their production

A strain of influenza virus, especially human influenza type A or B, for use in formulating a vaccine is selected by a process which comprises isolating candidate influenza viruses in embryonated hens' eggs, determining whether they have antigenic similarities to strains which are the same except that they have been isolated and grown exclusively in animal cells, that is to say whether they are 'cell-like', and selecting at least one such cell-like strain or a reassortant thereof having its HA and NA genes for the vaccine.

Influenza vaccine

Growing community of inventors

London, United Kingdom

John Sidney Oxford