California Institute of Technology

John S Pezaris

Richard A Andersen

Maneesh Sahani

A chronic chamber microdrive (&ldquo;CCMD&rdquo;) for neural recording. In one implementation, a CCMD for neural recording from a target site of neural tissue exposed by an opening in a skull of a subject, includes: an outer cylinder, having a longitudinal axis, positioned within the opening and rotatable within the opening; an inner cylinder positioned within the outer cylinder, such that the longitudinal axis of the outer cylinder is within a circumference of the inner cylinder and the inner cylinder rotates within the rotatable outer cylinder; at least one fine leadscrew, positioned longitudinally in the inner cylinder; at least one electrode for neural recording, where at least one of said electrodes is coupled to a corresponding one of said fine leadscrews, where said electrodes are positioned horizontally by rotating the outer cylinder and separately rotating the inner cylinder, and where said electrodes are positioned vertically by rotating said fine leadscrews.

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Pasadena, CA, United States of America

John S Pezaris