Pocared Diagnostics Ltd.

Battelle Memorial Institute

Cytyc Corporation

Other

John S Laudo

William Godwin Atterbury

Gal Ingber

Thomas Alan Klausing

John P Tallarico

Dave Holley

Jason A Schaefer

Sherwood G Talbert

David J Zahniser

Douglas E Boyd

Garrick L Maenle

Matthew S Zelinski

Russell H Barnes

Thomas M Dolash

K Bryan Scott

Carol Stillman

Amy M Heintz

Steven Risser

Thomas D Haubert

Alexander Morrow

Steve Grimes

Jonathan Gurfinkel

Steven E Huckaby

Joseph D Dennis

Mark Fleming

Kevin Sadeski

John Tallarico

Erik W Edwards

Herbert S Bresler

Eric R Navin

Albert E Iii Weller

The present invention relates to a system for conducting the identification and quantification of micro-organisms, e.g., bacteria in biological samples. More particularly, the invention relates to a system comprising a cooling, heating and fan arrangement for maintaining a predetermined optimum temperature of the samples during testing; a visual, circumferential and axial alignment system for aligning the samples within the carousel; a transfer system for transferring the samples from the carousel to the centrifuge; a balancing system of minimizing the rotational vibrations of the centrifuge; a safety system and anti-tipping design for the sample containing system; liquid dispensing arms for dispensing the buffered saline solution; and discharge ports for discharging and disposing of the liquid removed from the samples to a location external of the system.

System for conducting the identification of bacteria in biological samples

The present invention relates to a system for conducting the identification and quantification of micro-organisms, e.g., bacteria in biological samples. More particularly, the invention relates to a system comprising a disposable cartridge and an optical cup or cuvette having a tapered surface; an optics system including an optical reader and a thermal controller; an optical analyzer; a cooling system; and an improved spectrometer. The system may utilize the disposable cartridge in the sample processor and the optical cup or cuvette in the optical analyzer.

A system for conducting the identification and quantification of micro-organisms, e.g., bacteria in urine samples which includes: 1) several disposable cartridges for holding four disposable components including a centrifuge tube, a pipette tip having a 1 ml volume, a second pipette tip having a 0.5 ml volume, and an optical cup or cuvette; 2) a sample processor for receiving the disposable cartridges and processing the urine samples including transferring the processed urine sample to the optical cups; and 3) an optical analyzer for receiving the disposable cartridges and configured to analyze the type and quantity of micro-organisms in the urine sample. The disposable cartridges with their components including the optical cups or cuvettes are used in the sample processor, and the optical cups or cuvettes containing the processed urine samples are used in the optical analyzer for identifying and quantifying the type of micro-organism existing in the processed urine samples.

System for conducting the identification of bacteria in urine

Methods and devices for altering the power of a lens, such as an intraocular lens, are disclosed. In one method, the lens comprises a single polymer matrix containing crosslinkable pendant groups, wherein the polymer matrix increases in volume when crosslinked. The lens does not contain free monomer. Upon exposure to ultraviolet radiation, crosslinking causes the exposed portion of the lens to increase in volume, causing an increase in the refractive index. In another method, the lens comprises a polymer matrix containing photobleachable chromophores. Upon exposure to ultraviolet radiation, photobleaching causes a decrease in refractive index in the exposed portion without any change in lens thickness. These methods avoid the need to wait for diffusion to occur to change the lens shape and avoid the need for a second exposure to radiation to lock in the changes to the lens.

Methods for tailoring the refractive index of lenses

The invention describes a novel thermoelectric composite material containing electrically conductive polymeric fibrils in a polymer matrix with a high thermoelectric coefficient. The invention also includes a thermoelectric device using the composite. The invention also includes a thermoelectric device containing a thermoelectric layers and a thermoelectric device in which a thermal barrier isolates a thermoelectric layer from a structurally supporting substrate. The thermoelectric devices can be used to generate electricity or to control temperature.

Thermoelectric device and thermoelectric generator

Optical cup

A microscope system ('&#x2033;) includes a laser () or light emitting diode (&#x2032;&#x2033;) that generates source light having a non-uniform spatial distribution. An optical system includes an objective () defining a field of view, and an optical train (&#x2032;&#x2033;) configured to convert the source light into an enlarged-diameter collimated light, to spatially homogenize the enlarged-diameter collimated light, and to couple the homogenized enlarged-diameter collimated light into the objective to provide substantially uniform static illumination of the field of view. A camera system () is statically optically coupled by the objective with at least most of the field of view.

Optical system for cell imaging

Cartridge

Growing community of inventors

Columbus, OH, United States of America

John S Laudo