Pacific Biosciences of California, Inc.

Pendulum Therapeutics, Inc.

Whole Biome Inc.

John S Eid

Colleen Cutcliffe

Stephen Wilson Turner

Geoffrey Alan Otto

Jonas Korlach

Daniel Bernardo Roitman

Devon Murphy

Robin A Emig

Paul Hardenbol

James H Bullard

Marcus F Schicklberger

Jon M Sorenson

Kenneth Mark Maxham

Kevin Travers

Benjamin A Flusberg

Patrick Marks

Orville G Kolterman

Cheryl Heiner

Fred C Christians

Paul S Peluso

Donald M Gray

Adrian Nielsen Fehr

Jeremy Gray

Lei Sun

Geoff Otto

Alex Dewinter

Tomer Altman

David R Rank

Stephen P Dudek

Steven Lin

Mark Chaisson

Robert Sebra

Ravi Dalal

Paul McMurdie

Nicholas Justice

Surabhi Tyagi

Jessica Gines

Andrew T Cheng

Christian Sieber

The disclosure provides compositions and methods for therapeutic administration of the compositions to treat comorbidities associated with gut dysbiosis. The disclosure also provides compositions and methods for increasing engraftment of administered microbes. The disclosure also provides methods for stool sample collection.

Methods and compositions for microbial engraftment

Disclosed herein are methods and compositions for treatment of a microbiome associated disorder. Further, disclosed herein are methods and compositions for modulating short chain fatty acid production in a subject.

Methods and compositions for treatment of microbiome associated disorders

The present disclosure provides methods, systems, compositions, and kits to address the need for microbiome-related treatment of health conditions and disease. The present disclosure provides for treatment of metabolic conditions using microbial compositions.

Methods and compositions relating to microbial treatment and diagnosis of disorders

Methods and compositions for treatment of microbiome-associated disorders

Methods, devices, and systems for performing intermittent detection during analytical reactions are provided. Such methods facilitate collection of reaction data from disparate reaction times. Further, such methods are useful for reducing photo-induced damage of one or more reactants in an illuminated analytical reaction at a given reaction time. In preferred embodiments, the reaction mixture is subjected to at least one illuminated and non-illuminated period and allowed to proceed such that the time in which the reaction mixture is illuminated is less than a photo-induced damage threshold period.

Intermittent detection during analytical reactions

The present disclosure provides methods for profiling a microbiome and therapeutic compositions for treatment. Additionally, the methods, systems, compositions and kits provided herein are directed to assessing or predicting health status in a subject. Some of the embodiments include generating a report.

Methods and systems for microbiome characterization, monitoring and treatment

Nucleic acid sequence analysis

Growing community of inventors

San Francisco, CA, United States of America

John S Eid