Handylab, Inc.

Pure Green Pharmaceuticals, Inc.

Core Biosystems Inc.

Quantum Micromaterials, Inc.

John S Althaus

Kalyan Handique

Sundaresh N Brahmasandra

Betty Wu

Nikhil Phadke

Gene Parunak

Aaron Kehrer

Cecelia Haley

Ted Springer

Lee Kyonghoon

Vijay Namasivayam

Sung-Chan Jo

Stephen Goldner

Kyonghoon Lee

Hyung Jin Park

Kyong Hoon Lee

Debra Kimless

Gareth M Fotouhi

Shinnosuke Inoue

Myoung-Han Kim

This application features a method of forming a polymer layer on the surface of a substrate using a self-initiating monomer. A polymer layer is formed by polymerization of a monomer on a metal layer to fill or cover defects of the metal layer. The metal layer the polymer layer may be used as an airtight material.

Coating substrate by polymerization of amine compound and apparatus having polymer coated substrate

A composition includes n-acyl ethanolamine, at least one cannabinoid, and at least one terpene. The composition may be in the form of a tablet.

Tablet or composition having n-acyl ethanolamine and cannabinoid

Methods and systems for processing polynucleotides (e.g., DNA) are disclosed. A processing region includes one or more surfaces (e.g., particle surfaces) modified with ligands that retain polynucleotides under a first set of conditions (e.g., temperature and pH) and release the polynucleotides under a second set of conditions (e.g., higher temperature and/or more basic pH). The processing region can be used to, for example, concentrate polynucleotides of a sample and/or separate inhibitors of amplification reactions from the polynucleotides. Microfluidic devices with a processing region are disclosed.

Method for processing polynucleotide-containing samples

System for processing polynucleotide-containing samples

Disclosed herein is a substrate-independently surface-coated polymer by aromatic-amine compound and a coating method thereof, and in particular to a substrate-independently surface-coated polymer and a coating method thereof wherein an aromatic compound in which two or more amines are substituted on benzene, is substrate-independently surface-coated. The substrate-independently surface-coated polymer characterized in that the surface of a polymer substrate is coated in such a way to react, using a surface modifier, an aromatic compound of the following structural formula on at least one surface of the polymer substrate having a nucleophilic functional group or an electrophilic functional group.

Substrate-independently surface-coated polymer by aromatic-amine compound and coating method thereof

Methods and systems for processing polynucleotides (e.g., DNA) are disclosed. A processing region includes one or more surfaces (e.g., particle surfaces) modified with ligands that regain polynucleotides under a first set of conditions (e.g., temperature and pH) and release the polynucleotides under a second set of conditions (e.g., higher temperature and/or more basic pH). The processing region can be used to, for example, concentrate polynucleotides of a sample and/or separate inhibitors of amplification reactions from the polynucleotides. Microfluidic devices with a processing region are disclosed.

Processing polynucleotide-containing samples

The present invention relates to an electrochemical method for detecting a target polynucleotide. An electrode comprising an electrode surface is provided. The electrode surface includes at least one probe molecule reversibly immobilized with respect to the electrode surface. A first electrochemical signal indicative of an amount of probe molecule immobilized with respect to the electrode surface is obtained. The electrode surface is contacted with a liquid comprising the target polynucleotide. Upon the contacting step, at least some of the probe molecule immobilized with respect to the electrode surface dissociates therefrom. A second electrochemical signal indicative of an amount of probe molecule immobilized with respect to the electrode surface is obtained. The presence of the target polynucleotide is determined at least partially on the basis of the first and second electrochemical signals.

System and method for electrochemical detection of biological compounds

Growing community of inventors

Saline, MI, United States of America

John S Althaus