Nimbus, Incorporated

University of Pittsburgh

Intelligent Hearing Systems

John Robert Boston

James F Antaki

Kenneth C Butler

Douglas C Thomas

Seongjin Choi

Rafael E Delgado

Abreena Iris Tlumak

John David Durrant

Devin V Amin

The present invention relates to methods and systems for profiling evoked potentials in brain electrical activity which apply steady state response concepts to analysis of longer latency responses reflective of activity of brain regions beyond the brainstem, up to an including the cortex. The use of repeated stimuli within a single analysis window produces a quasi steady-state response and permits a high-resolution spectral analysis. Response amplitudes were measured at repetition rates from 80 to below 1 Hz, using trains of repeated tone-burst stimuli. An amplitude measure introduced and defined as the harmonic sum was incorporated into the spectral power of the response carried by both the fundamental frequency, and the harmonics thereof. Additionally, time ensemble averaging can be employed to improve signal to noise ratio.

Steady state measurement and analysis approach to profiling auditory evoked potentials from short-latency to long latency

An automatic speed control system continually adjusts the speed of an implanted cardiac assist blood pump to an optimum level for the varying physiological needs of the patient. It does this by periodically iteratively incrementing the speed setpoint of the pump. When the system detects the imminence of a ventricular collapse at diastole, it decrements the speed setpoint by a predetermined safety margin. An alarm condition is provided if the setpoint decrease results in an insufficient blood flow rate through the pump. The flow rate and imminence of ventricular collapse are computed in real time as functions of only the pump's motor current and speed setpoint.

Speed control system for implanted blood pumps

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Wexford, PA, United States of America

John Robert Boston