Varian Medical Systems, Inc.

Zap Surgical Systems, Inc.

Accuray Inc.

Other

Leland Stanford Junior University

Varian Medical Systems Particle Therapy Gmbh

John R Adler

Achim Schweikard

James Edward Clayton

M Bret Schneider

Radhika Mohan Bodduluri

Jianing Shi

Younes Achkire

Kaustubh Sonawale

Manoocher Birang

Hui Zhang

David H Whittum

Steven W Prince

Raymond Wilbur

Chris C Lee

Agam Sharda

Yun-Yi Ting

Cesare Jenkins

Tom McDermott

Doyle John Borchers, Iii

Cheng-Chieh Tsai

Jin-Wu Wang

Thilaka S Sumanaweera

Gary H Glover

Yan-Ling Liu

Ralf Bruder

Floris Ernst

Ya-Shan Lin

Dezhi Liu

Hongwu Wang

Ben Chen

Bernadette Seijo

Tzu-Cheng Yu

Sandy A Napel

Michele Borchers, Legal Representative

Ying-Jhang Chen

Thomas McDermott

Ron Boeder

Thomas Hopmans

Thibaut Loysel

Methods of treatment and treatment systems for performing radiomodulatory stereotactic radiosurgery to treat brain disorders in which target neural tissues associated with the brain disorder are sensitized to radiation by administration of a molecular substance and/or non-targeted critical structures are protected from radiation by a molecular substance, in order to treat disorders of brain circuitry. Specific embodiments disclose means for treating pain, obesity and drug addiction.

Radiosurgical neuromodulation close to critical structures

Devices and methods that allow a user to elect between performing treatment planning by inverse planning or to be accomplished by utilizing one or more parameters input that are typically associated with forward planning are described herein. The systems can be configured to produce a treatment plan in a single iteration upon initiation of treatment planning or in response to determining or receiving a target geometry. While the system may be used iteratively in an extensively interactive fashion, viable inverse plans can be generated with a single user interaction, such as a single click, or optionally with no click at all. Advantageously, the system can optionally allows a clinician to add or adjust parameters or constraints, for example in another iteration, to provide additional autonomy if desired.

Inverse planning device and methods for radiation treatment

A self-shielded and computer controlled system for performing non-invasive stereotactic radiosurgery and precision radiotherapy using a linear accelerator mounted within a two degree-of-freedom radiation shield coupled to a three-degree of freedom patient table is provided. The radiation shield can include an axial shield rotatable about an axial axis and an oblique shield independently rotatable about an oblique axis, thereby providing improved range of trajectories of the therapeutic and diagnostic radiation beams. Such shields can be balanced about their respective axes of rotation and about a common support structure to facilitate ease of movement. Such systems can further include an imaging system to accurately deliver radiation to the treatment target and automatically make corrections needed to maintain the anatomical target at the system isocenter. Various subsystems to automate controlled and coordinated movement of the movable shield components and operation of the treatment related subsystems to optimize performance and ensure safety are also provided.

Imaging systems and methods for image-guided radiosurgery

Systems and methods for real-time target validation during radiation treatment therapy based on real-time target displacement and radiation dosimetry measurements.

Systems and methods for real-time target validation for image-guided radiation therapy

A method includes determining skin characteristics in a region of a patient. An in-treatment optical scan is performed on a region of a patient, wherein the in-treatment optical scan comprises a near infrared (NIR) energy source. A plurality of detected signals is detected from the optical scan. The skin characteristics are filtered out from the plurality of detected signals. Skeletal anatomy positioning associated with the region is determined from the plurality of signals that is filtered.

NIR image-guided targeting

Therapeutic radiation beam detector for radiation treatment systems

Removable marker implants having fiducial markers disposed on multiple elongate members extend and splay laterally outward when deployed thereby providing improved 3D localization and tracking of a portion of the patient's body for stereotactic radiosurgery. Such an approach is particularly useful for tracking of the uterus during radiosurgery treatment of uterine fibroids. Such implants can include an outer sheath that contains the multiple elongate members during delivery into the portion of the body. The elongate members can be slidably disposed within the shaft and advanced into an expanded deployed position by advancement of an applicator shaft or rod within the sheath. Marker implant can also be integrally formed implants with flexible arms having fiducial markers thereon that can be constrained in a sheath for delivery and resiliently splay laterally outward when released from the shaft. Methods of delivery and deployment are also provided.

Device for radiosurgical treatment of uterine fibroids

Display screen or portion thereof with graphical user interface for a radiation treatment

A method for measuring skin thickness. The method includes at a first 3D point on an outer surface of a patient, exposing the first point to near infrared (NIR) energy from an NIR source. The method includes measuring reflected energy emanating near the first 3D point, or beam incident point. The method includes determining a pattern of the reflected energy based on a distance from a center of the reflected energy, wherein the center is approximated by the first 3D point. The method includes determining a skin thickness measurement based on the pattern.

Apparatus and method for real-time tracking of bony structures

Growing community of inventors

Stanford, CA, United States of America

John R Adler