Wyeth

John Potoski

Arthur G Mohan

Wayne G McMahon

Panolil C Raveendranath

Silvio Iera

Sreenivasulu Megati

Galina Vid

Jean Louise Helom

Christopher Demerson

Maria Papamichelakis

Vladimir Dragan

Jacqueline F Lunetta

Michael F MacEwan

Bogdan Kazimierz Wilk

Donna Mary Huryn

Arwinder Singh Nagi

Arkadiy Zinoviy Rubezhov

Ramarao S Chatlapalli

John Leo Considine

Zhixian Ding

Gulnaz Khafizova

Xinxu Shi

Weiguo Liu

Antonia Nikitenko

Alexander V Gontcharov

Micronized tanaproget, purified tanaproget Form I, and micronized, purified tanaproget Form I are provided. Also provided are compositions containing one or more of the prepared tanaproget forms, methods of using one or more of the prepared tanaproget forms, and kits containing one or more of the prepared tanaproget forms.

Purified form of tanaproget

Methods of making Gonadotropin Releasing Hormone ('GnRH') (also known as Leutinizing Hormone Releasing Hormone) receptor antagonists, comprising reacting a compound having Formula I: with a compound having formula L&#x2014;(CRR)&#x2014;D, are disclosed.

Processes for preparing gonadotropin releasing hormone receptor antagonists

This invention relates to a process for the preparation of 6-hydroxyequilenins, which are useful as estrogenic agents.

Preparation of 6-hydroxyequilenins

The present invention provides processes for the preparation of compounds of Formula I, which are useful in the preparation of pharmaceuticals for the treatment of inflammatory diseases. The compounds of Formula I are also useful as pharmaceuticals. 

Processes for the preparation of 2-cyano-3-naphthalene-1-yl-3-phenyl-propionic acid alkyl or benzyl esters

The present invention provides processes for the preparation of substituted naphthylindole derivatives that can be used as inhibitors of plasminogen activator inhibitor-1(PAI-1). In certain embodiments of the invention, the processes involve reactions that include one or more of an Oppenauer oxidation, a Fischer indole synthesis, a methyl ether cleavage, or coupling a substituted methyltetrazole with a substituted naphthol.

Processes and compounds for the preparation of substituted naphthylindole derivatives

The present invention provides a new process and intermediates for the production of antiviral compound 4',4-bis-{4,6-bis-[3-(bis-carbamoyl-methyl-1-sulfamoyl)-phenylamino]-[1,3,5]triazin-2-ylamino}-biphenyl-2,2&#x2032;-disulfonic acid and its pharmaceutically acceptable salts.

Preparation and purification of antiviral disulfonic acid disodium salt

The present invention provides a new process and intermediates for the production of antiviral compound 4&prime;,4-bis-&lcub;4,6-bis-&lsqb;3-(bis-carbamoyl-methyl-1-sulfamoyl)-phenylamino&rsqb;-&lsqb;1,3,5&rsqb;triazin-2-ylamino&rcub;-biphenyl-2,2&prime;-disulfonic acid and its pharmaceutically acceptable salts.

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West Nyack, NY, United States of America

John Potoski