R.j. Reynolds Tobacco Company

Rai Strategic Holdings, Inc.

Brown & Williamson Tobacco Corporation

Niconovum Usa, Inc.

Modoral Brands Inc.

Brown & Williamson Holdings, Inc.

John-Paul Mua

Andries Don Sebastian

Stephen Benson Sears

Rajesh Sur

Michael F Davis

Billy Tyrone Conner

Pankaj C Patel

Kyle Ford

Darrell Eugene Holton, Jr

Barry Bratcher

Joshua D Morton

Anthony Richard Gerardi

Daniel Verdin Cantrell

Thaddeus Jude Jackson

Luis Monsalud

Gong Chen

Samuel Mark Debusk

Crystal Dawn Hege Byrd

Vahid Hejazi

Frank Kelley St Charles

Michael Francis Dube

Eric Taylor Hunt

Evon Llewellyn Crooks

Barry Smith Fagg

Paul Andrew Brinkley

Nicholas Harrison Watson

Dwayne William Beeson

Melissa Ann Clark

David Neil McClanahan

John Howard Robinson

Cynthia Stewart Stokes

Jeremy Barrett Mabe

Serban C Moldoveanu

Alvaro Gonzalez-Parra

Paul G Hoertz

Timothy Franklin Tilley

S Keith Cole

James Neil Figlar

Nicholas Partain

Leigh Ann Blevins Joyce

Margarette Elisa Lovette

Leigh Hagan

Luis Rosete Monsalud, Jr

Brian Keith Nordskog

Donna Walker Duggins

Yan Pu

Matthew William Benford

David Troy Turfler

Matthew E Lampe

William R Conway

Darrell D Williams

Kenneth John Bradley, Jr

Chelsea Allison Cooke

Laya Katina Palmer

Christopher Keller

Cheryl Cooper Scott

Samantha S White

Karter R Yutzy

Walter M Drexler

Darrell Holton

Jennifer Rowe

Terence McGeown

Chelsea Allison Betts

Brad L Hayes

Terryl V Baker

Karen Womble Wallace

Barbara Walker Arzonico

Chelsea Alison Betts

Stephen Cole

Jr Darrell Eugene Holton

Jack Flinchum

Jr Luis R Monsalud

Alan Benson Norman

Rodney Dean Schluter

A method of modifying the moisture level of (e.g., dehydrating) a tobacco plant or portion thereof, a tobacco-derived material, a tobacco product, or a tobacco additive is provided herein. The methods of dehydration disclosed herein can provide various benefits relative to traditional drying techniques, including providing retention of various beneficial components present in green tobacco (e.g., organoleptic compounds and proteins). Smoking articles and other tobacco products including such dehydrated tobacco materials are also provided.

Dehydration of tobacco and tobacco-derived materials

The invention provides a multi-layered smokeless tobacco product comprising two or more formulations with varying properties. In some embodiments, the smokeless tobacco products provide combinations of different organoleptic properties within the same product. In certain embodiment, these combinations allow for a modified release profile of active ingredients as the user enjoys the smokeless tobacco product. The invention further provides methods for making and using the smokeless tobacco product.

Multi-layer smokeless tobacco composition

The present disclosure provides protein-enriched, tobacco-containing products, suitable for use as oral formulations. Products of the present disclosure typically include at least one tobacco material (e.g., a particulate tobacco material or a tobacco-derived extract), at least one protein-enriched material (e.g., a tobacco-derived protein-enriched material), and at least one sugar alcohol.

Protein-enriched tobacco composition

The present disclosure provides aerosol delivery devices. In an example implementation, an aerosol delivery device comprises an aerosol source member that defines an outer surface and an interior area and includes a substrate material having an aerosol precursor composition associated therewith, a control body having a housing that is configured to receive the aerosol source member, an electrical energy source coupled with the housing, and a heating assembly operatively connected to the electrical energy source. The heating assembly includes a plurality of spikes that may be configured to articulate between a retracted position, in which the plurality of spikes is not in contact with the aerosol source member, and a heating position, in which the plurality of spikes pierces through the outer surface of the substrate material and into a portion of the interior area thereof.

Aerosol delivery device with conductive inserts

The disclosure describes methods for the purification of protein-enriched extracts to provide concentrates and isolates and methods for incorporation of such materials into products. The purification methods are adapted for removal of nicotine and may have other benefits, e.g., lightening the color of the protein-enriched extracts. The methods generally include treatment with peracetic acid or hydrogen peroxide and filtrations. A protein composition in the form of a concentrate or isolate is provided, the protein composition including RuBisCO, F2 fraction proteins, or combination thereof extracted from a plant of thespecies, wherein the protein composition is characterized by relatively low nicotine content.

Purification of tobacco-derived protein compositions

The invention provides a smokeless tobacco composition adapted for oral use, the composition including a tobacco material and an effervescent material. The effervescent material includes a sugar material containing an entrapped gaseous component, such that release of the entrapped gaseous component occurs upon dissolution of the sugar material in the oral cavity. The invention also provides a method for making a smokeless tobacco composition that involves mixing a tobacco material with an effervescent material, the mixing step including either admixing a granulated composition comprising a tobacco material with a gasified sugar material in particulate form, or forming a gasified sugar material in situ by mixing a water source with a molten composition comprising a tobacco material and a sugar alcohol.

Smokeless tobacco product comprising effervescent composition

The disclosure describes methods for the purification of protein-enriched extracts to provide concentrates and isolates and methods for incorporation of such materials into products. The purification methods are adapted for removal of one or more of ash, metal salts, alkaloids, particulates, heavy metals, and other impurities and/or contaminants from extracts, as well as modifying the sensory characteristics (e.g., odor, color, and/or taste characteristics) of extracts. The methods generally include diafiltration, treatment with functionalized resins, and supercritical extraction. A protein composition in the form of a concentrate or isolate is provided, the protein composition including RuBisCO, F2 fraction proteins, or combination thereof extracted from a plant of thespecies, wherein the protein composition is characterized by one or more of: an ash content of less than about 15% by weight; a nicotine content of less than about 10 μg/g, and a heavy metal content of less than about 60 μg/g.

Tobacco-derived protein compositions

The disclosure describes methods for the purification of protein-enriched extracts to provide concentrates and isolates and methods for incorporation of such materials into products. The purification methods are adapted for removal of, e.g., chlorophyll and may thus provide lightening the color of the protein-enriched extracts. The methods generally include treatment with peracetic acid or hydrogen peroxide and filtrations. A protein composition in the form of a concentrate or isolate is provided, the protein composition including RuBisCO, F2 fraction proteins, or combination thereof extracted from a plant material.

Plant-derived protein purification

The present disclosure describes methods of obtaining and/or deriving proteins from plants of thespecies and methods for incorporation of such proteins into various products. For example, a method for obtaining a protein-enriched material from a plant of thespecies or portion thereof is provided, comprising: extracting one or more proteins from the plant material into a solvent to form a liquid protein-containing extract; separating a solid extracted plant material from the liquid protein-containing extract; clarifying the liquid protein-containing extract to form a clarified protein-containing extract and a solids fraction; and treating the clarified protein-containing extract so as to provide a protein-enriched material comprising at least about 60% protein by weight.

Protein-enriched tobacco-derived composition

The present disclosure provides an aerosol delivery device comprising an aerosol source member. In an example embodiment, an aerosol source member of the present disclosure may comprise a substrate portion comprising a nanocellulose material impregnated with an aerosol precursor composition, a heat source configured to heat the aerosol precursor composition from the substrate portion forming an aerosol, and an aerosol pathway extending from the substrate portion to a mouth-end of the aerosol delivery device.

Aerosol delivery device with nanocellulose substrate

Growing community of inventors

Advance, NC, United States of America

John-Paul Mua