Depuy Synthes Products, Inc.

Valo Health, Inc.

Depuy Spine, Inc.

Dolby Laboratories Licensing Corporation

Telecommunication Systems, Inc.

Goodfield Energy Corporation

Integral Health, Inc.

John Paul Griffin

Jennifer DiPietro

John Riley Hawkins

Sean P Selover

Michael J O'Neil

Brian Raimundo

Elena S Koltun

Eric Stangeland

Hassan A Serhan

William J Frasier

Namal Nawana

Jonathan Bellas

Matthew Parsons

Christopher L Ramsay

Roman Lomeli

Zoher S Bootwala

Christopher Andrew Nordstrom

Cody Cranson

Mark T Hall

Nicholas Pavento

Joseph Hernandez

Douglas Raymond

William C Horton

Martin A Reynolds

John Dieselman

Michelle LeClerc

Mary Louise Fowler

Max Reinhardt

Lisa Gilman

Michelle LaWare

Glenn N Dickins

Michael Andrew Slivka

Kevin Lee

Gordon John Hines

David D Konieczynski

Dennis Chien

Lance Douglas Pitt

Michael C Gorhan

Thomas E Martin

Robert E Sommerich

Mark Gracia

James Paiva

Seungkyu Daniel Kwak

Hiroaki Kondo

Aldon R Reinhardt

James J Roveda

Aya Itokawa

Lori L Solomon

Matthew A Tullis

Provided herein are compounds, compositions including them, and methods of modulating GPR120 activity and treating diseases mediated by GPR120 by administering such compounds and compositions.

Monocyclic compounds useful as GPR120 modulators

Bicyclic compounds useful as GPR120 modulators

Various systems and methods are provided for surgical and interventional planning, support, post-operative follow-up, and functional recovery tracking. In general, a patient can be tracked throughout medical treatment including through initial onset of symptoms, diagnosis, non-surgical treatment, surgical treatment, and recovery from the surgical treatment. In one embodiment, a patient and one or more medical professionals involved with treating the patient can electronically access a comprehensive treatment planning, support, and review system. The system can provide recommendations regarding diagnosis, non-surgical treatment, surgical treatment, and recovery from the surgical treatment based on data gathered from the patient and the medical professional(s). The system can manage the tracking of multiple patients, thereby allowing for data comparison between similar aspects of medical treatments and for learning over time through continual data gathering, analysis, and assimilation to decision-making algorithms.

Systems and methods for surgical and interventional planning, support, post-operative follow-up, and, functional recovery tracking

Methods, systems, and devices are provided for guiding surgical instruments using radio frequency (RF) technology. In general, the methods, systems, and devices can allow a trajectory, e.g., an angular approach, of a surgical instrument relative to a patient to be identified during use of the instrument in a surgical procedure being performed on the patient. The trajectory can be identified using a plurality of RF modules. The methods, systems, and devices can allow the trajectory to be compared to a predetermined trajectory so as to identify whether the trajectory matches the predetermined trajectory. A result of the matching can be communicated to a user of the instrument. Based on the result, the user can maintain the trajectory, e.g., if the trajectory matches the predetermined trajectory, or can adjust the trajectory to closer align the trajectory with the predetermined trajectory, e.g., if the trajectory does not match the predetermined trajectory.

Methods, systems, and devices for guiding surgical instruments using radio frequency technology

An expandable trial can include an inferior portion, a superior portion, and a middle expanding portion as well as load cells for monitoring the load on the trial. The trial may also include recesses on its lateral sides to provide spacing to accommodate a disc removal tool so tissue can be cleared monitoring load. In addition, neural foramen spacing can be monitoring to provide information about how much neural release has been achieved as the disc is cleaned and the spine is positioned and repositioned.

Methods and devices for spinal correction

Systems and methods for surgical and interventional planning, support, post-operative follow-up, and functional recovery tracking

Various systems and methods are provided for surgical and interventional planning, support, post-operative follow-up, and functional recovery tracking. In general, data related to retraction of tissue can be gathered during performance of a surgical procedure. In one embodiment, the data can be used during performance of the surgical procedure, e.g., to determine whether a length of time a tissue is retracted using a retractor reaches a predetermined threshold amount of time, an amount of tissue retraction reaches a predetermined amount of tissue, and an amount of pressure being placed on tissue and/or nerves as a result of retraction reaches a predetermined amount of pressure, and/or the data can be used after performance of the surgical procedure, e.g., in determining a correlation between the data and patient pain level data.

A persona-notitia intellection codifier (P-NIC) server intelligently codifies and disburses personal user information from a user device (smartphone, laptop, etc.) to a multiplicity of designee devices. Masking Persona-Notitia Intellection Codes (a.k.a. PICs) are created that each stipulate control(s) and parametric limitation(s) for the associated one of a variety of personal user information. The Persona-Notitia Intellection Codifier (P-NIC) server rapidly produces a mask comprising a multiple bit 'key' value (i.e., a persona-notitia intellection code (PIC)) that is uniquely distinguishable from every other PIC that's ever been generated for a given user. The value of the PIC is typically many bytes in length, and associates attributes to a unique key value that describes a desired subset of all the user's available personal user information to be unlocked by the key value (i.e., by the PIC).

Persona-notitia intellection codifier

Growing community of inventors

Boston, MA, United States of America

John Paul Griffin