Pioneer Hi-bred International, Inc.

John P Mathis

Thomas Chad Wolfe

Catherine J Clark

Jennifer Kara Barry

Terry EuClaire Meyer

Weiping Xie

Xiaohong Zhong

Azalea S Ong

Amy Lum

Ryan Michael Gerber

Brooke Peterson-Burch

Nasser Yalpani

Deirdre M Kapka-Kitzman

Andre R Abad

Takashi Yamamoto

Ruth Cong

Jingtong Hou

James M Hasler

Mark Edward Nelson

Naga Kishore Kakani

Song Leng

Claire Marie Bazyk

Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.

Insecticidal proteins from plants and methods for their use

The disclosure relates to insecticidal toxin resistance management and screening of novel insecticidal toxins. One embodiment relates to the isolation, characterization, compositions, and methods of use relating to polynucleotides encoding novel insecticidal toxin receptors and the polypeptides encoded thereby. The polynucleotides and polypeptides are useful in identifying or designing novel insecticidal toxin receptor ligands including novel insecticidal toxins.

Insecticidal toxin receptors and methods of use

The invention provides nucleic acids, and variants and fragments thereof, obtained from strains ofencoding polypeptides having pesticidal activity against insect pests, including. Particular embodiments of the invention provide isolated nucleic acids encoding pesticidal proteins, pesticidal compositions, DNA constructs, and transformed microorganisms and plants comprising a nucleic acid of the embodiments. These compositions find use in methods for controlling pests, especially plant pests.

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The invention relates to Bt toxin resistance management. The invention particularly relates to the isolation and characterization of nucleic acid and polypeptides for a novel Bt toxin receptor. The nucleic acid and polypeptides are useful in identifying and designing novel Bt toxin receptor ligands including novel insecticidal toxins.

The invention relates totoxin resistance management. The invention particularly relates to the isolation and characterization of nucleic acid and polypeptides for a noveltoxin receptor. The nucleic acid and polypeptides are useful in identifying and designing noveltoxin receptor ligands including novel insecticidal toxins.

Growing community of inventors

Des Moines, IA, United States of America

John P Mathis