Origin Medsystems, Inc.

Boston Scientific Scimed, Inc.

Maquet Cardiovascular LLC

Barosense, Inc.

Maui Imaging, Inc.

Synecor LLC

Sherwood Services Ag

Endosphere, Inc.

Xlumena, Inc.

Oxular Limited

Covidien LP

Applied Medical Resources Corporation

Covidien Ag

Ancora Heart, Inc.

Hvr Cardio Oy

John P Lunsford

Albert K Chin

William L Athas

Richard S Stack

Daniel J Balbierz

Richard Glenn

Charles Gresl, Jr

Kevin H Van Bladel

Tenny Chang

Kenneth F Binmoeller

Fiona Maria Sander

Edwin J Hlavka

Thomas A Kramer

Dan Balbierz

Samuel T Crews

Charles J Adam

Daniel T Wallace

Michael Scott Williams

Jeffrey A Smith

Liming Lau

John W Davis

Michael C Stewart

Michael Francis Wei

Donald Francis Specht

Lee Bolduc

Kenneth D Brewer

David M Smith

Andrew C Smith

Lee R Bolduc

Fred E Silverstein

Shuji Uemura

Nathan Every

Robert Steven Bley

Dwight P Morejohn

Frederic H Moll

David H Cole

Harry Leonard Green, Ii

Bretton Mark Swope

Geoffrey H Willis

John D Davis

Loc X Phan

Stanley R Conston

Joshua K Wallin

David Michael Cole

Mariel Fabro

Olli Keränen

Jeffrey Wayne Baxter

Hoang Phan

Brian A Hodges

Tim McCoy

William S Eubanks

Sharon L Adam

Harry Ino

Richard Kouri

Ashik A Mohan

David J Specht

Joseph N Lamberti

Peter L Callas

Robert James Mosley

James T McKinley

Brett Swope

Tien Thuy Nguyen

Edmund J Roschak

Edward A Pineda

Ronald K Yamamoto

Jon M Tanaka

Iris Leon Corbin

Hoang G M Phan

Christopher Thorne

Dillon Daniel Martinez

Robert H Hawes

Dana G Mead

David B McCallum

William S Eubanks, Jr

Dave Cole

Brian Tang

Peter Tachi Callas

Tim J Kovac

Eugene Serina

Benjamin Sherman

Sammy S Datwani

Tammy Y Tam

Bryan E Loomas

John T To

Theodore A Richardson

Tenny C Calhoun

Stephen Clark Meier

Stephen Olson

Jon Sherman

Sam Crews

Richard A Glenn

Nam Q Nguyen

Edwin J Heavka

Stacy Patch

Adrian Borlan

MingYao Ding

Young M Kang

Andrew Smith

Robert T Hawes

Kevin To

Transluminal access system includes a stent delivery catheter having a handle control mechanism. The catheter comprises a number of components for establishing an initial penetration between adjacent body lumens and subsequently implanting a stent or other luminal anchor therebetween. Manipulation of the stent components is achieved using control mechanisms on the handle while the handle is attached to an endoscope which provides access to a first body lumen.

Apparatus and method for deploying stent across adjacent tissue layers

Described herein are methods for reversibly constraining an endoscope. A method may include positioning an elongate medical device or endoscope in a holder of a clamp. A method may include actuating the holder such that one or more of a first sidewall and a second sidewall of the holder move to a clamped configuration to exert a force on the endoscope. A method may include adjusting a pad of the clamp from a first position to a second position where the pad is in contact with the endoscope in the second position.

Endoscope control methods

The present invention provides a drug composition comprising particles comprising a biodegradable or bioerodable polymer and a drug, a soluble, biodegradable or bioerodible excipient, a bulking agent and a reconstitution aid. The invention also provides a pharmaceutical formulation and a unit dosage form of the pharmaceutical formulation. The invention provides methods of treatment of a disease or condition accordingly. The invention also provides a drug composition for use in a cannulation device.

Ophthalmic drug compositions

An intragastric device includes an elongated member having a proximal end and a distal end and an anchor connected to the elongated member. The anchor includes a stem, a first arch and a second arch, and a curvilinear element. The stem includes a proximal end and a distal end. The distal end of the stem is attached to the proximal end of the elongated member. Each arch has first and second ends and a proximal peak therebetween. The first end of each arch is attached to the proximal end of the stem, and the second end of each arch extends radially away from the stem. The curvilinear element connects the second end of the first arch to the second end of the second arch.

Duodenal gastrointestinal devices and related treatment methods

Described herein are devices for reversibly constraining an endoscope. Such devices may comprise: a base positionable proximate a patient; a column extending vertically from the base; an arm extending horizontally from the column; and a clamp coupled to the arm. In some embodiments, the clamp comprises a holder comprising an annular ring defining an endoscope receiving area or a first sidewall and a second sidewall together defining an endoscope receiving area. The holder is transitionable between a first configuration in which the annular ring or the first and second sidewall are configured to set apart from an endoscope in the endoscope receiving area and a second configuration in which the annular ring or the first and second sidewall are configured to clamp the endoscope in the endoscope receiving area.

Endoscope control devices

Described herein are various embodiments of flexible catheters comprising one or more flexibility regions. In one embodiment, a catheter comprises an elongate body having a proximal segment and a distal segment; a first lumen defined by the elongate body and configured for drainage of a liquid from a bodily region; and a plurality of flexibility regions on or in the distal segment of the elongate body. The plurality of flexibility regions, collectively, is configured to passively bend anteriorly. Further, at least one of the plurality of flexibility regions has a defined percent volume of material removed and a defined cut depth percentage. The features and arrangement of the flexibility regions described herein result in the catheter requiring reduced force during insertion into a bodily lumen.

Flexible catheters and related methods

A system for delivering an endolumenal device through an endoscope includes a delivery tool and an adaptor. The delivery tool has an elongate tube configured to hold a portion of the endolumenal device therein and a first connecting feature on a distal end of the elongate tube. The adaptor is configured to attach to a handle of the endoscope. The adaptor includes a channel therethrough and a second connecting feature configured to mate with the first connecting feature of the delivery tool. The elongate tube of the delivery tool is configured to align with the channel of the adaptor when the first and second connecting features are mated.

Duodenal gastrointestinal devices and delivery mechanisms

Sterile lyophilized drug compositions and methods for treating ocular diseases or conditions

A method of calibrating an ultrasound probe includes mounting an ultrasound probe onto a calibration system, transmitting an ultrasound test signal from an element of the probe through a test medium of the calibration system, and receiving the test signal on a matrix of hydrophones such that an element's position relative to other elements and other arrays within the same probe can be computed. Further, the system described herein is configured to detect the acoustic performance of elements of a probe and report the results to an end user or service provider.

Calibration of ultrasound probes

Described herein are endoscopic plicators passed transorally into the stomach and used to plicate stomach tissue by engaging tissue from inside of the stomach and drawing it inwardly. In the disclosed embodiments, the tissue is drawn inwardly into a vacuum chamber, causing sections of serosal tissue on the exterior of the stomach to be positioned facing one another. The disclosed plicators allow the opposed sections of tissue to be moved into contact with one another, and preferably deliver sutures, staples or other means for maintaining contact between the tissue sections at least until serosal bonds form between them. Each of these steps may be performed wholly from the inside of the stomach and thus can eliminate the need for any surgical or laparoscopic intervention. After one or more plications is formed, medical devices may be coupled to the plication(s) for retention within the stomach.

Endoscopic plication devices and methods

The present application describes an implant system useable for positioning an implant device such as a device useful for restricting passage of ingested food into the stomach. In one embodiment, the disclosed system includes a plurality of anchors that may be coupled to tissue within the stomach, or to a tissue tunnel formed by plicating stomach wall tissue. The anchor includes a loop. During use, the implant device is inserted through the loop and expanded such that it retains its position within the loop until removed. Instruments for implanting and explanting the implant device are also described.

Systems and methods related to gastro-esophageal implants

Growing community of inventors

San Carlos, CA, United States of America

John P Lunsford