St Jude Medical, Atrial Fibrillation Division, Inc

John P Goetz

Thomas Blake Eby

John William Sliwa

Jennifer Teng

Andrew M Radin

John Edwards Crowe

Steven C Christian

Stephen A Morse

Zhenyi Ma

Frank Callaghan

Vera S Boudtchenko

Vera S Boudtchenka

A transition apparatus for use with a medical device having an elongate element is disclosed. The apparatus may include a body defining a lumen for housing at least a portion of the elongate element. The body may have a proximal end configured for releasable connection to the medical device and a distal end. The apparatus may further include a connection piece connected to the distal end of the body. The connection piece may have a first opening configured to receive the elongate element from the lumen of the body and a second opening configured to receive the elongate element from the first opening and direct the elongate element toward the body. A method of connecting a transition apparatus to an ablation device having a leash is also disclosed.

Transition apparatus for use with a medical device having an elongate element

A tissue ablation apparatus includes a body having at least two lumens extending therethrough and an ultrasound ablation element positioned within a distal region of the body. The ultrasound ablation element includes an ultrasound transducer and a membrane. One of the lumens is arranged so as to deliver a fluid into a cavity defined between the transducer and the membrane. A first orifice is provided in the body proximal of the ultrasound ablation element and is open to the first lumen to define a first vacuum pathway. A distal vacuum chamber, opening to a second orifice in the body, is defined by the body distal of the ultrasound ablation element and is in communication with the first lumen to define a second vacuum pathway. At least one flow control apparatus is provided to regulate flow through one of the vacuum pathways independent of flow through the other vacuum pathway.

Vacuum-stabilized ablation system

A tissue ablation system facilitates lesioning deep tissue while preventing damage to superficial tissue and includes a probe having a distal end portion, at least one transducer carried on the distal end portion, and at least one acoustically transparent heat removal element thermally coupled to a target tissue within the beam path of the transducer. The transducer delivers acoustic energy to the tissue through the heat removal element in order to ablate the tissue; the heat removal element removes sufficient thermal energy from the tissue volume to prevent thermal necrosis in superficial tissue. The heat removal element may be a heat sink or a convective element. An optional temperature sensor provides advisory data to a practitioner and/or is coupled to a feedback control system operable to control delivery of acoustic energy to the tissue and/or a rate of thermal energy removal therefrom.

Apparatus and method for tissue ablation with near-field cooling

A carrier for an ablation element is provided. The carrier includes a plurality of walls defining a receiving portion configured to receive at least a portion of an ablation element. A plurality of connection formations are disposed on an exterior surface of least one of the plurality of walls. Each of the plurality of connection formations is disposed at a different vertical position of the carrier. A device for epicardial ablation is also provided. The device includes a plurality of carriers disposed adjacent to each other. Each carrier includes a plurality of walls defining a receiving portion configured to receive at least a portion of an ablation element. A plurality of connection formations are disposed on an exterior surface of at least one of the plurality of walls of each carrier. Each of the plurality of connection formations is disposed at a different vertical position of a carrier.

Universal cell carrier

A focused ultrasound transducer includes a first ultrasonic emitter and at least one metallic ultrasonic lens acoustically coupled thereto. The emitter generates ultrasonic energy that propagates along a beam path projecting therefrom. The at least one metallic ultrasonic lens is positioned at least partially in the beam path so that it can direct (e.g., focus, defocus, and/or collimate) in at least one direction (or along at least one plane) at least some of the ultrasonic energy propagating from the emitter. The metallic lens may be formed by extrusion, by molding (e.g., diecast molding or thermoforming), or by sintering (e.g., powder metallurgy). The metallic lens also advantageously functions as a heat sink, improving thermal performance of the ultrasound transducer.

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Aptos, CA, United States of America

John P Goetz