Medigene Ag

Universitaet Zu Koeln

Ludwig-maximilians-universitaet

John Nieland

Michael Hallek

Markus Hoerer

Luca Perabo

Mirko Ritter

Hildegard Buening

Kerstin Lux

Jorge Boucas

Kerstin Pinotossi

Daniela Kuehn

Markus HÖRER

Daniela KÜHN

Hildegard BÜNING

The present invention is related to a structural protein of a parvovirus with an amino acid insertion at the insertion site I-453, a library comprising the protein, a multimeric structure comprising the protein, a nucleic acid encoding the protein, a vector, virus or cell comprising the nucleic acid, a process for the preparation of the protein, a medicament comprising the protein, nucleic acid or multimeric structure as well as methods and uses involving the protein, nucleic acid or multimeric structure.

Mutated structural protein of a parvovirus

The present invention is related to a method for identifying a parvovirus mutated structural protein capable of specifically binding to a binder for an antigen, a parvovirus mutated structural protein which comprises at least one B-cell epitope heterologous to the parvovirus, a multimeric structure comprising the protein, a nucleic acid encoding the protein, a virus or cell comprising the protein, a method of preparing the protein, a medicament comprising the protein, nucleic acid or multimeric structure and its use.

Mutated parvovirus structural proteins as vaccines

The present invention is related to a structural protein of a parvovirus with an amino acid insertion at the insertion site I-453, a library comprising the protein, a multimeric structure comprising the protein, a nucleic acid encoding the protein, a vector, virus, or cell comprising the nucleic acid, a process for the preparation of the protein, a medicament comprising the protein, nucleic acid, or multimeric structure as well as methods and uses involving the protein, nucleic acid, or multimeric structure.

Growing community of inventors

Aarhus C, Denmark

John Nieland