Sirna Therapeutics, Inc.

Ribozyme Pharmaceuticals, Incorporated

John Min

Leonid Beigelman

Jasenka Matulic-Adamic

David Sweedler

Peter Haeberli

Mark Reynolds

Nilabh Chaudhary

Alexander Karpeisky

Alex Karpeisky

This invention features permeability enhancer molecules, and methods, to increase membrane permeability of various molecules, such as nucleic acids, polynucleotides, oligonucleotides, enzymatic nucleic acid molecules, antisense nucleic acid molecules, 2-5A antisense chimeras, triplex forming oligonucleotides, decoy RNAS, dsRNAs, siRNAs, aptamers, or antisense nucleic acids containing nucleic acid cleaving chemical groups, peptides, polypeptides, proteins, carbohydrates, steroids, metals and small molecules, thereby facilitating cellular uptake of such molecules.

Compositions for the delivery of negatively charged molecules

This invention features permeability enhancer molecules, and methods, to increase membrane permeability of negatively charged polymers thereby facilitating cellular uptake of such polymers.

Growing community of inventors

Longmont, CO, United States of America

John Min