University of Virginia Patent Foundation

Johnson and Johnson Vision Care, Inc.

John Mcgrath

Edward R Kernick

Vincent Henri Barre

Leslie A Voss

Dominic P Gourd

Nathan Swami

Walter Varhue

Vahid Farmehini

Carlos Honrado

Yi Liu

Sydney Higginbottom

An exemplary method and system is disclosed that facilitate the integration of multiplexed single-cell impedance cytometry in a high throughput format, which can be deployed upstream from microfluidic sample preparation and/or downstream to microfluidic cell separation. In exemplary method and system may employ impedance-based quantification of cell electrophysiology on the same microfluidic chip (i.e., 'on-chip') to provide distinguishing phenotypic information on the sample, without the need for additional sample handling, preparation or dilution steps as would be needed for other flow cytometry techniques.

Multiplexed on-chip impedance cytometry system and method

Growing community of inventors

Charlottesville, VA, United States of America

John Mcgrath