Shockwave Medical, Inc.

Incon-trol Corp.

Calibra Medical, Inc.

Philip Morris Inc.

Endogastric Solutions, Inc.

Cardiac Dimensions, Inc.

Empire Technology Development LLC

Philip Morris USA Inc.

Medtronic, Inc.

Cardiac Pacemakers, Inc.

Other

Siemens Aktiengesellschaft

The Coca-cola Company

Philip Morris Products S.a.

Key Safety Systems, Inc.

John Mathew Adams

Clifton A Alferness

Daniel Hawkins

Brett J Carter

Doug Hakala

Stefan J M Kraemer

Thomas G Goff

Reginald W Newsome

Donald H Evers

Randy Holmberg

Robert E Talley

Christopher N Chance

Michael A Kirby, Sr

David G Reuter

Steve G Baker

James A DeBlasio

Mark L Mathis

William C Harris, Jr

Khoi Le

Show-Mean Steve Wu

Kenneth R Infinger

Hoa D Nguyen

Xuan M Pham

Brett Cross

Leonard Kowalsky

Cruz Beeson

John R McKenzie

Travis Ryan Marsot

Gregory M Ayers

Wesley G Sanderson

John Melmoth Power

Scott J Wolf

John C Bayne

Jaeho Kim

Mohammad R Hajaligol

Phillip Dewey Foshee, Jr

Susan E Wrenn

Grier S Fleischhauer

Darrell Orvin Wagner

Mary Ellen Counts

Willie G Houck, Jr

Billy J Keen, Jr

Tommy C Holland

David Moir

Raymond Michael Wolniewicz, Iii

Ronald R Stewart

Naohisa Tsukamura

Robert Gallino

Frederick M Della Crosse

Barry Scott Smith

Joseph M Bocek

Jay A Fournier

Hugo Xavier Gonzalez

Charles T Higgins

John Bryant Paine, Iii

Michael L Watkins

Douglas A Burton

Harley G White

Daniel Yerkovich

William J Crowe

Rajesh Gopalaswamy

Horst Belau

Robert L Ripley

Robert E Lee

Jeffrey I Seeman

David E Sharpe

Constance H Morgan

William A Sirokman

Patrick H Hayes

Stephen T Vincent

Angel Amendola

Kenneth B Shepard

Jeffrey M Haskin

John R Hearn

Francis M Sprinkel

Michael S Braunshteyn

Paul Citron

Kenneth S Houghton

Zuyin Yang

William T Griffin

H Neal Nunnally

Wynn R Raymond

Donald H Jones

James D Baggett, Jr

Brett W Stevenson

Paul E Kreyenhagen

Charles W Harris

Constance Morgan

Donald B Losee, Jr

John D Naworal

Werner Kaiser

Yixuan Jin

Mikhail S Braunshteyn

Brian P Akers

Stefan Jm Kraemer

William P Taylor

Edward J Woolridge

Jeffrey M Haskins

Described herein are shock wave devices and methods for the treatment of calcified heart valves. One variation of a shock wave device includes three balloons that are each sized and shaped to fit within a concave portion of a valve cusp when inflated with a liquid and a shock wave source within each of the three balloons. Each balloon is separately and/or independently inflatable, and each shock wave source is separately and/or independently controllable. Methods of treating calcified heart valves using a shock wave device can include advancing a shock wave device having one or more balloons and a shock wave source in each of the balloons to contact a heart valve, inflating the one or more balloons with a liquid such that the balloon is seated within a concave portion of a valve cusp, and activating the shock wave source.

Shock wave valvuloplasty with multiple balloons

Disclosed herein shock wave catheters comprising one or more shock wave electrodes for cracking calcifications located within blood vessels. In some variations, a shock wave catheter has first and second shock wave electrodes each circumferentially disposed over the outer surface of the catheter. In certain variations, the first electrode has a recess and the second electrode has a protrusion that is received by the recess and a spark gap is located along the separation between the recess and the protrusion. The second electrode can also have a recess that receives a protrusion from a third shock wave electrode, where the separation between the second and third electrodes along the separation between the recess and the protrusion forms a second spark gap. A shock wave can be initiated across these spark gaps when a voltage is applied over the electrodes.

Shock wave electrodes

Described herein are low-profile electrodes for use with an angioplasty shockwave catheter. A low-profile electrode assembly may have an inner electrode, an insulating layer disposed over the inner electrode such that an opening in the insulating layer is aligned with the inner electrode, and an outer electrode sheath disposed over the insulating layer such that an opening in the outer electrode sheath is coaxially aligned with the opening in the insulating layer. This layered configuration allows for the generation of shockwaves that propagate outward from the side of the catheter. In some variations, the electrode assembly has a second inner electrode, and the insulating layer and outer electrode may each have a second opening that are coaxially aligned with the second inner electrode. An angioplasty shockwave catheter may have a plurality of such low-profile electrode assemblies along its length to break up calcified plaques along a length of a vessel.

Low profile electrodes for an angioplasty shock wave catheter

A system includes a catheter including an elongated carrier, a balloon about the carrier in sealed relation thereto, the balloon being arranged to receive a fluid therein that inflates the balloon, and first and second electrodes within the balloon arranged to carry a voltage there-across including an initial high electrical voltage at an initial low current. The initial high electrical voltage causes an electrical arc to form across the first and second electrodes within the balloon. The electrical arc causes a gas bubble within the liquid, a high current to flow through the first and second electrodes, a decrease in the initial high electrical voltage, and a mechanical shock wave within the balloon. The system further includes a power source that provides the first and second electrodes with a drive voltage that creates the initial high electrical voltage at the initial current and that terminates the drive voltage in response to the decrease in the initial high electrical voltage.

Shock wave catheter system with energy control

An apparatus includes a balloon adapted to be placed adjacent a calcified region of a body. The balloon is inflatable with a liquid. The apparatus further includes a shock wave generator within the balloon that produces shock waves that propagate through the liquid for impinging upon the calcified region adjacent the balloon. The shock wave generator includes a plurality of shock wave sources distributed within the balloon.

Shock wave balloon catheter with multiple shock wave sources

A valvuloplasty system comprises a balloon adapted to be placed adjacent leaflets of a valve. The balloon is inflatable with a liquid. The system further includes a shock wave generator within the balloon that produces shock waves. The shock waves propagate through the liquid and impinge upon the valve to decalcify and open the valve.

Shockwave valvuloplasty catheter system

A system that breaks calcium in a liquid includes a catheter including first and second electrodes arranged to receive there-across a high electrical voltage at an initial low current. The high electrical voltage causes an electrical arc to form across the electrodes creating a gas bubble within the liquid, a high current to flow through the electrodes, and a mechanical shock wave. A power source provides the electrodes with the high electrical voltage at the initial current and terminates the high electrical voltage in response to the high current flow through the electrodes.

Shockwave catheter system with energy control

A system for breaking obstructions in body lumens includes a catheter including an elongated carrier, a balloon about the carrier in sealed relation thereto, the balloon being arranged to receive a fluid therein that inflates the balloon, and an arc generator including at least one electrode within the balloon that forms a mechanical shock wave within the balloon. The system further includes a power source that provides electrical energy to the arc generator.

Shockwave balloon catheter system

A transoral gastroesophageal flap valve restoration device has sufficient flexibility and dimension to be passed through the mouth, throat, and esophagus of a patient into the patient's stomach. The device includes a first member and a second member hingedly coupled to the first member. The first and second members are configured to flex in a direction to follow the esophageal path into the stomach and to be substantially rigid when forming the restored gastroesophageal flap valve.

Flexible transoral endoscopic gastroesophageal flap valve restoration device and method

Growing community of inventors

Snohomish, WA, United States of America

John Mathew Adams