Other

Leland Stanford Junior University

John Martin Brown

Amato J Giaccia

Nigel P Minton

Grant Leonard Parker

Sam Rahman

Adarsh Pun

Shie-Chau Liu

James Magner

Jim Magner

Recombinant anaerobic bacterial compositions that under anaerobic conditions present in a solid tumor and produce an enzyme capable of catalyzing the conversion of a prodrug to its cytotoxic product in situ are described. Methods of treating tumors using the composition are also described.

Anaerobe targeted enzyme-mediated prodrug therapy

A genetically-engineered anaerobic organism is provided which, under anaerobic conditions present in a solid tumor, produces an enzyme capable of catalyzing the conversion of a prodrug to its highly cytotoxic product in situ and methods of treating tumors using same.

Anaerobe targeted enzyme mediated prodrug therapy

Security equipment protects the relaying of account numbers and personal identification numbers (PIN) by telephonic or other communication link. The equipment includes a host computer an a remote portable transaction device that interact. A credit granting institution generates an account number and a series of unique personal identification numbers for each account number. This information is stored in the host computer's memory and is assigned as a reference series to an individual customer account number. An identical series of numbers in the same sequence is stored in the memory of the remote device. In operation, the customer account on the host computer is activated and the host computer's memory is indexed sequentially to the first number in the reference series. During the use of the remote device, a unique personal identification number is added to the customer account number and transmitted to the host computer. There it is compared to the account number and personal identification number in the reference series. The computer will authorize the transaction if the number in the stored series is identical the number in the reference series. Otherwise the transaction will be denied or questioned.

Transaction device, equipment and method for protecting account numbers

A secure credit card 10 has a body member to which is attached a microprocessor controller 14 electrically coupled a Programmable Read Only Memory (PROM) device 18 programmed with a series of random numbers in a predetermined sequence. The random numbers are identical to random numbers in a host computer and in the identical sequence as the random numbers in the host computer. This computer is accessible upon each use of the credit card 10. The Programmable Read Only Memory (PROM) accesses the next random number in sequence with each use of the credit card 10 to permit verification by comparing the random number with each use of the credit card 10 with the next random number in sequence as indicated by the computer. A switch 20 actuated with each use of the credit card 10 provides a pulse signal that activates the microprocessor controller 14 to turn on the Programmable Read Only Memory (PROM) to access the next random number in the sequence. A counter 26 connected to the microprocessor controller 14 counts the number of pulse signals received to count each use of the credit card 10. A display device 24 displays the next Personal Identification Number (PIN) in the sequence each time a pulse is received.

Secure credit card which prevents unauthorized transactions

A finishing tool providing a smooth finish to taped coved joints or to corner joints having an angle greater than 90.degree. defined by converging wall board surfaces is presented. The finishing tool includes a working plate and a supporting plate, each being provided with a substantially straight edge disposed transversely to the longitudinal axes of the tool. Each of the working and supporting plates is formed of resilient material to provide longitudinal and latitudinal flexural movement so as to allow the entire length of the straight edge of the working plate to engage seam sealing material applied to the corner joint and the adjacent wall board surfaces to provide a smooth continuous finish to the corner joint.

Growing community of inventors

Redwood City, CA, United States of America

John Martin Brown