Isis Innovation Limited

University of Utah Research Foundation

John Mark Lupton

Paul Leslie Burn

Ifor David William Samuel

Richard Beavington

Michael H Bartl

Debansu Chaudhuri

Jeremy Galusha

Nicholas Borys

Manfred Josef Walter

Systems and methods for performing transmission microscopy on a sample material are disclosed. The sample material is placed on a metal nanoparticle substrate. High intensity light, such as an infrared laser, is focused on the nanoparticle substrate, thereby exciting the silver nanoparticles. The excited nanoparticles emit intensely focused, spectrally broad white light that is able to pass through the sample material without significant scattering even when the sample material is highly diffuse. The emitted light that passes through the sample material is detected and used to generate images and characterize features of the sample material, including the internal structural composition of the sample material.

Transmission microscopy using light emitted from nanoparticles

A compound of formula (I), where x is 3, 2 or 1, y is 0 or 1, nand n, which may be the same or different, are 0 or 1 to 3, X represents a divalent mono- or poly-aromatic and/or heteroaromatic moiety, the or each Y, which may be the same or different if x is 1, represents hydrogen or an optionally substituted hydrocarbon group, Z represents an aromatic group, or an inherently at least partly conjugated dendritic molecular structure comprising one or more aromatic and/or heteroaromatic groups and, optionally, alkenylene groups, connected to each other either directly or via a carbon atom of an alkenylene group, if present, to a ring carbon atom of an (hetero) aromatic group to which more than one at least partly conjugated dendritic chain is attached, said molecular structure being connected to the remainder of the molecule via a ring carbon atom, one or more of the (hetero) aromatic rings of the dendrimers optionally being substituted, Z and/or the remainder of the molecule, excluding any groups Y, being luminescent, with the proviso that when Z represents an aromatic group y must be 1.

Dendrimers

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Salt Lake City, UT, United States of America

John Mark Lupton