Waters Technologies Corporation

John Maillet

Joshua A Shreve

Paul B Keenan

Ryan M Hill

A thermal system for use in a column manager of a liquid chromatography system comprises a plurality of spatially separated individually controlled thermoelectric chips. A column module houses a plurality of thermally conductive troughs. Each trough resides in a separate thermal zone to be thermally conditioned individually by one of the individually controlled thermoelectric chips. Each trough is adapted to hold one or more liquid chromatography columns therein. A plurality of spatially separated thermal bridges includes a first thermal bridge thermally coupling one of the thermoelectric chips to a first one of the plurality of troughs and a second thermal bridge of the plurality of thermal bridges thermally coupling another of the thermoelectric chips to a second one of the plurality of troughs.

Column manager with a multi-zone thermal system for use in liquid chromatography

Exemplary embodiments are directed to apparatus, systems and methods used in connection with a needle valve device operating in a pressurized flow system. The apparatus, systems and methods provide for automatic positioning of a needle relative to a seat in the needle valve device to provide consistent calibration with minimal user interaction after a maintenance event or upon a start-up of the pressurized flow system. The apparatus, systems and methods utilize a calibration collar secured to a shaft of an actuator within the needle valve device. The calibration collar includes one or more locking mechanism and a spring.

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Hudson, MA, United States of America

John Maillet