Louisiana State University and Agricultural & Mechanical College

The General Hospital Corporation

Ergo Science Incorporated

Ergo Research Corporation

Cyncron Corporation

The Board of Supervisors of Louisana State and Agricultural and

John M Wilson

Albert H Meier

Anthony H Cincotta

A method for increasing chick production by increasing the level of L-DOPA in the bloodstream of breeder hens is described. Chick production is increased by increasing rates of egg laying, fertility of laid eggs, and number of fertile eggs that hatch. Methods for reducing the effects of stress on egg laying by increasing the level of L-DOPA in the bloodstream of breeder hens are also described.

Method for increasing productivity in breeder hens

A method for reducing the total fat and cholesterol contents and the ratio of saturated to unsaturated fatty acids and for increasing total protein content in eggs produced by animals is described. The level of L-Dihydroxyphenylalanine (L-DOPA) in the bloodstream of the poultry is elevated so as to cause the animals to produce eggs which have a reduced cholesterol content and eggs which have a lower ratio of saturated to unsaturated fatty acids. In a preferred embodiment the L-DOPA is orally administered to poultry by incorporation in the food for said poultry.

Method of altering the contents of eggs

This invention relates to methods for regulating or ameliorating lipid metabolism which comprise administration or timed administration of inhibitors of dopamine beta hydroxylase (DBH).

Method for regulating metabolism with dopamine beta hydroxylase

This invention relates to a method for modifying metabolism in a vertebrate animal which entails the administration of pantethine or cysteamine at a predetermined time daily. The method is useful in the treatment of hyperglycemia, glucose intolerance, insulin resistance, and hyperinsulinemia.

Method for regulating glucose metabolism

Disclosed are methods for improving various aberrant metabolic indices in mammals including humans by administration of muscarinic (particularly M1) receptor antagonists alone or in combination with prolactin inhibiting compounds. Preferably the administration takes place at a predetermined time (or, if a combination of muscarinic receptor antagonist and prolactin inhibitor is used, at different predetermined times) during a 24-hour period when the administration is effective (or its effect more pronounced). The invention has application in the treatment of lipid and glucose metabolism disorders.

Administration of pirenzepine, methyl scopolamine and other muscarinin

Administration of pirenzepine, methyl scopolamine and other muscarinic

A method for reducing the total fat and cholesterol contents and the ratio of saturated to unsaturated fatty acids and for increasing total protein content in eggs produced by animals is described. The level of n-Dihydroxyphenylalanine (L-DOPA) in the bloodstream of the poultry is elevated so as to cause the animals to produce eggs which have a reduced cholesterol content and eggs which have a lower ratio of saturated to unsaturated fatty acids. In a preferred embodiment the L-DOPA is orally administered to poultry by incorporation in the food for said poultry.

A process is provided for activating reproduction in seasonal breeding vertebrates during normally non-reproductive seasons by administering L-dihydroxyphenylalanine (L-DOPA), thereby increasing the level of L-DOPA in the vertebrate's bloodstream to a reproductively active level. An effective amount of 5-HTP can also be injected into the vertebrate followed, an effective period of time later, with an injection of an effective amount of L-DOPA.

Process for activating reproduction in seasonal breeding animals by

Disclosed herein are methods for regulating or ameliorating lipid and glucose metabolism and reducing in a vertebrate animal body fat stores, insulin resistance, hyperinsulinemia, hyperglycemia, hyperlipidemia, elevated blood lipoproteins (such as triglycerides and cholesterol including chylomicrons, VLDL and LDL) and/or increasing in the subject the plasma HDL. The methods comprise administration or timed administration of inhibitors of dopamine beta hydroxylase (DBH).

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Charlestown, MA, United States of America

John M Wilson