Alphamed Pharmaceuticals Corp.

Alphamed Pharmaceutical Corp.

Other

Protease Sciences Inc.

World Pharmaceutical Trust

World-pharm Trust

Alphamed Pharaceutical Corp.

John Lezdey

Darren Lezdey

K Anne Kronis

Jarett R Lezdey

Darren B Lezdey

There is provided a two component polyurethane coating system which contains anti-microbial complexes consisting of phenol complexes which provide anti-microbial characteristics to the coating system and improved abrasion resistance. There is also provided substrates coated with the antimicrobial coatings.

Antimicrobial coatings

Anti-microbial compositions, polymers and paints having incorporated therein at least one phenolic complex. Preferably a chloroxylenol complex is utilized for topical treatment of a patient with a bacterial or viral skin infection.

Anti-microbial compositions and polymers

Alpha 1-antitrypsin is prepared by growing in a fermentor methylotropic yeast transformants containing in their genome at least one copy of DNA encoding alpha 1-antitrypsin, in operational linkage with DNA encoding a signal sequence, which is effective for directing secretion of proteins from the host cells, DNA constructs and recombinant yeast strains used for the expression and secretion of alpha 1-antritrypsin are also provided. The fermentation medium requires a pH of 6.5 to 7.5. The fermentation is at a pH between 5 and 6.8.

DNA for expression of alpha 1-antitrypsin in methylotropic yeast

An examination or surgical glove having an inner coating of a compound which prevents the degranulation of mast cells which releases medicators of inflammation. The coating includes anti-mast cell and anti-inflammatory agents such cromolyn compounds and human type protease inhibitors.

Surgical and examination gloves

The present invention relates to the treatment of cancerous conditions in mammals by the administration to the site of disease compositions containing serine protease inhibitor. The cancerous conditions include osteocarcinomas, melanoma, Karopsi sarcoma and keratosis. The compositions are also useful to relieve the pain associated with the disease.

Treatment of osteocarcinoma with alpha-1&mdash;antitrypsin or secretory leucocyte protease inhibitor

Topical wound therapeutic compositions

The present invention provides for the treatment of a patient suffering from a collagen related disease utilizing a serine protease inhibitor. The treatment includes the use of a corticosteroid that is administered separately or in combination. The serine proteases preferred are alpha 1-antitrypsin, alpha 2-macroglobulin and secretory leucocyte protease inhibitor.

Treatment of collagen related diseases

The present invention provides a method and composition for treating eye and ear inflammation and eye and ear infections. The compositions contain a cromolyn compound alone or in combination with a corticosteroid. A steroidal antiphlogistic compound, a non-steroidal antiphlogistic compound and optionally hyaluronic acid may be added.

Cromolyn for eye and ear infections

The present invention provides for the treatment of an individual suffering from infections from herpes virus or human papilloma virus by utilizing a cromolyn compound. The treatment includes the use of a corticosteroid or L-lysine that can be administered separately or in combination.

Method for treating infectious viral diseases

Cosmetic compositions and methods are provided for revitalizing the skin especially where it is placed in an environment that can cause injury to the skin. The compositions contain an effective amount of cromolyn compounds to provide a prophylactic or repairing effect.

Cosmetic compositions containing cromolyn compounds for revitalizing the skin

Cosmetic compositions and methods are provided for revitalizing the skin especially where it is placed in an environment that can cause injury to the skin. The compositions contain an effective amount of a serine protease inhibitor to reduce damage to the skin resulting from exposure to the sun.

Cosmetic compositions containing serine protease inhibitors

A cat litter composition is provided which contains on the litter particles an antimicrobial composition, which is the admixture of a diquat, a polycarboxylic acid, at least one phenol compound and a carrier, which is water or alcohol-water.

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Indian Rocks Beach, FL, United States of America

John Lezdey