Fisons Ltd.

John L Hart

Andrew R Clark

John S Corbett

Geraldine Walkley

Kevan E Chippendale

Nicholas A Drought

A device for the administration by inhalation of a medicament in powdered form comprises a medicament reservoir (3) and metering means for dispensing a dose of medicament from the reservoir (3), characterized in that the reservoir (3) comprises a compacted body of powdered medicament (10) and the metering means includes means (11) for abrading the compacted body (10).

Medicament inhalation device and formulation

A compacted body of powdered medicament for use in a device for the administration by inhalation of a medicament in powdered form. The compacted body is made by compressing a loose powder containing the medicament in powdered form under pressure to create sufficient structural integrity in the body to permit metering of several unit doses of the medicament by abrasion of the body in the device.

An elastomeric cap for use in an aerosol inhalation device is disclosed. The cap prevents blockage and the buildup of accretions of medicament on the valve stem of the inhalation device and shields the valve stem from the breath of a user of the inhalation device.

Inhalation devices with a reduced risk of blockage

An aerosol inhalation device, having a mouthpiece (12) and a canister (15) of pressurized hygroscopic medicament, the canister (15) being fitted at one end with a dispensing metering valve; wherein a protective barrier (19) is provided between the dispensing metering valve and the mouthpiece (12) so as to eliminate or substantially reduce blockage of the device.

A method of compacting and administering a powdered inhalation medicament for use in an inhalation device includes compacting a body of loosely powdered inhalation medicament such that the degree of compaction is sufficient to hold the body together solely due to the force of compaction and placing the compacted body into the inhalation device and abrading the compacted body to obtain a plurality of unit doses of the medicament.

A device for the administration by inhalation of a medicament in powdered form. The device includes a supply of the medicament in the form of a compacted body of powered medicament, a rotatable helical blade which abrades a desired quantity of the medicament from the compacted body, and a mouthpiece through which the abraded powder can be inhaled by the user of the device.

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Bramcote, United Kingdom

John L Hart