Visx, Inc.

Amo Manufacturing Usa, LLC

Advanced Medical Optics, Inc.

John Karl Shimmick

Charles R Munnerlyn

Kingman Yee

Terrance N Clapham

William B Telfair

Stephen J Hinkson

Seema Somani

Herrmann J Glockler

Stephen J Koons

Jerome A Legerton

Vladimir Lemberg

Richard A Hofer

George Caudle

Kenneth Greenberg

Marc Odrich

Jason Paul Watson

Lawrence W Stark

Ioan T Oltean

Herrmann J Glocker

Jerry Legerton

A method for measuring an optical system comprises transmitting an image with the optical system. Gradients of the optical system can be determined by separating the transmitted image with a lenslet array. An error-correcting change in the shape of the optical system can be mapped by integrating across the gradients. The change in elevation around the path is related to the accuracy of the gradient array. A system for measuring a wavefront of an eye includes an image source for projecting an image into the eye, lenslets, a detector for measuring angles of light rays of an optical surface of an eye, and a computer for mapping the errors of the eye. A tomographic wavefront map is made by deflecting the measurement path of the wavefront sensor. Aberrations are selected for treatment in response to an order of the aberration and a tissue structure corresponding to the aberration.

Direct wavefront-based corneal ablation treatment program

An ophthalmological surgery system and method for performing ablative photodecomposition of the corneal surface by offset image scanning. The image of a variable aperture, such as a variable width slit and variable diameter iris diaphragm, is scanned in a preselected pattern to perform ablative sculpting of predetermined portions of a corneal surface. The scanning is performed with a movable image offset displacement mechanism capable of effecting radial displacement and angular rotation of the profiled beam exiting from the variable aperture. The profiled beam is rotated by rotating the aperture in conjunction with the offset displacement mechanism. The invention enables wide area treatment with a laser having a narrower beam, and can be used in the treatment of many different conditions, such as hyperopia, hyperopic astigmatism, irregular refractive aberrations, post ablation smoothing and phototherapeutic keratectomy.

Method and system for laser treatment of refractive errors using offset imaging

Systems, methods and apparatus for performing selective ablation of a corneal surface of an eye to effect a desired corneal shape, particularly for correcting a hyperopic/astigmatic condition by laser sculpting the corneal surface to increase its curvature. In one aspect of the invention, a method includes the steps of directing a laser beam onto a corneal surface of an eye, and changing the corneal surface from an initial curvature having hyperopic and astigmatic optical properties to a subsequent curvature having correctively improved optical properties. Thus, the curvature of the anterior corneal surface is increased to correct hyperopia, while cylindrical volumetric sculpting of the corneal tissue is performed to correct the astigmatism. The hyperopic and astigmatic corrections are preferably performed by establishing an optical correction zone on the anterior corneal surface of the eye, and directing a laser beam through a variable aperture element designed to produce a rectangular ablation (i.e., cylindrical correction) on a portion of the optical correction zone. The laser beam is then displaced by selected amounts across the optical correction zone to produce a series of rectangular ablations on the correction zone that increases the curvature of the corneal surface to correct the hyperopic refractive error.

Systems and methods for corneal surface ablation to correct hyperopia

Systems and methods of the present invention measure at least one reflecting surface of an object disposed along an optical path. In some embodiments a measured optical interference signal for each of at least three wavelengths of reflected light may be used to determine a modulation of frequency components of a Fourier series. Frequency components of a Fourier series may be transformed to spatial components that describe intensities and positions of light reflected along an optical path. Systems and methods of the present invention permit rapid measuring and may monitor corneal thickness during surgery. The invention may do so by integrating an ablation device and a measurement apparatus into a single system. An integrated scanning and monitoring system may include an ablative light source producing an ablative beam and a measurement light source producing a measurement beam.

Integrated scanning and ocular tomography system and method

The present invention provides methods, systems, and apparatus for calibrating a laser ablation system, such as an excimer laser system for selectively ablating a cornea of a patient's eye. The invention also facilitates alignment of eye tracking cameras that measure a position of the eye during laser eye surgery. A calibration and alignment fixture for a scanning laser beam delivery system having eye tracking cameras may include a structure positionable in a treatment plane. The structure having a feature directing laser energy incident thereon to a calibration energy sensor, at least one reference-edge to determine a characteristic of the laser beam (shape, dimensions, etc.), and an artificial pupil to determine alignment of the eye tracking cameras with the laser system.

Methods and systems for laser calibration and eye tracker camera alignment

Systems and methods verify and/or correct optical errors of an eye. A plan is generated for a corrective procedure of the eye from a measured optical error, and a verification lens is formed based on the measured optical error to verify the procedure plan. Alignment of an aperture (with a size selected to correspond to the size of the pupil) with the eye while measuring optical properties of the eye through the verification lens improves verification accuracy, as does mounting of the verification lens and aperture to the patient with a trial frame.

Enhanced wavefront ablation system

An ophthalmic surgery system and method for treating presbyopia by performing ablative photodecomposition of the corneal surface. A laser system ablates tissue to a predetermined ablation shape, and the cornea heals significantly to form a multifocal shape correcting presbyopia. The multifocal shape corrects for near-vision centrally and far-vision peripherally. The system and method enables wide area treatment with a laser having a narrower beam than the treatment area, and can be used in the treatment of many conditions in conjunction with presbyopia such as hyperopia, hyperopic astigmatism and irregular refractive aberrations.

Method and systems for laser treatment of presbyopia using offset imaging

Systems, methods and apparatus for generating images of portions of the patient's eye, such as the anterior surface of the cornea. The methods and apparatus of the present invention are particularly useful for directly imaging the profile of the ablated region of the cornea during or immediately following a laser ablation procedure, such as photorefractive keratometry (PRK), phototherapeutic keratectomy (PTK), laser in-situ keratomileusis (LASIK) or the like. These methods and apparatus allow the surgeon to precisely image the exterior edge of the eye to characterize the profile of ablated corneas and to determine the spatial variance of tissue ablation rates during the surgical procedures. Methods and apparatus are also provided for generating one or more images depicting the profile of the ablated region of the cornea. The profile is registered with a pre-ablation profile to provide feedback regarding the true ablation properties of the eye. This feedback permits the laser system to be programmed with a laser ablation algorithm based on the measured ablation properties of the eye.

Systems and methods for imaging corneal profiles

Improved systems, devices, and methods measure and/or change the shape of a tissue surface, particularly for use in laser eye surgery. Fluorescence of the tissue may occur at and immediately underlying the tissue surface. The excitation energy can be readily absorbed by the tissue within a small tissue depth, and may be provided from the same source used for photodecomposition of the tissue. Changes in the fluorescence spectrum of a tissue correlate with changes in the tissue's hydration.

Hydration and topography tissue measurements for laser sculpting

Methods and devices for performing corrective eye surgery generally direct a laser beam at a target region of a patient's eye with the laser beam having a non-uniform energy distribution profile. As ablation rates vary locally across the beam cross-section, the energy distribution profile is tailored to effect a uniform ablation depth with each laser pulse of an excimer laser system.

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Belmont, CA, United States of America

John Karl Shimmick