Avexa Limited

University of Wollongong

John Joseph Deadman

David Ian Rhodes

Eric Dale Jones

Lisa Jane Winfield

Jonathan Alan Victor Coates

Neeranat Thienthong

Nicholas Andrew Van De Graff

William Issa

Neil Choi

Giang Thanh Le

Stephen Geoffrey Pyne

Paul Anthony Keller

Zinka Brkic

Nicholas Andrew Vandegraff

Mark James Robertson

Jody Morgan

Neal Kevin Dalton

Timothy Patrick Boyle

Katherine Macfarlane

Sebastian Mario Marcuccio

John Barnard Bremner

John Barnard Bremmer

Nicholas Andrew Vandegraaff

Widanagamage Ruwansiri Epa

Neeranat Theinthong

Katherinie Macfarlane

The present invention provides a compound of Formula I or a pharmaceutically acceptable derivative, salt or prodrug thereof. Further provided is a method of treatment or prophylaxis of a viral infection in a subject comprising administering to said subject an effective amount of a compound of Formula I or a pharmaceutically acceptable derivative, salt or prodrug thereof. A pharmaceutical composition or medicament comprising a compound of Formula I is also provided. 

Bicyclic pyrimidinones and uses thereof

The present invention provides a compound of formula (I) or a pharmaceutically acceptable derivative, salt or prodrug thereof. The present invention further provides a method of treatment or prophylaxis of a viral infection in a subject comprising administering to said subject an effective amount of a compound of formula (I) or a pharmaceutically acceptable derivative, salt or prodrug thereof. Pharmaceutical compositions comprising a compound of formula (I) are also provided.

Compounds having antiviral properties

The present invention provides a compound of formula I, II, III and IV as defined herein and pharmaceutically acceptable derivatives thereof. The present invention further provides use of the compounds of the present invention in the treatment of bacterial infection and in the treatment of HIV infection. Also provided are pharmaceutical compositions comprising the compounds of the present invention. 

Peptidic compounds

The present invention provides a compound of formula (I) or a pharmaceutically acceptable derivative, salt or prodrug thereof. The present invention further provides a method of treatment or prophylaxis of a viral infection in a subject comprising administering to said subject an effective amount of a compound of formula (I) or a pharmaceutically acceptable derivative, salt or prodrug thereof. Pharmaceutical compositions comprising a compound of formula (I) are also provided. 

Imidazopyrimidines and uses thereof

Compounds of formula (I) or a pharmaceutically acceptable derivative, salt or prodrug thereof are disclosed. Also disclosed are methods of treating a viral infection in a subject by administering to the subject an effective amount of a compound of formula (I) or a pharmaceutically acceptable derivative, salt or prodrug thereof. Pharmaceutical compositions comprising a compound of formula (I) are also provided. 

Thiazopyrimidinones and uses thereof

The present invention relates to a novel process for the chiral resolution of 2-substituted 4-substituted 1,3-oxathiolanes and derivatives thereof. The present invention also relates to novel 2-substituted 4-substituted 1,3-oxathiolanes derivatives.

Process for chiral resolution of 2-substituted 4-substituted 1,3-oxathiolanes

The present invention provides a compound of formula (I), (II), (III) and (IV) as defined herein and pharmaceutically acceptable derivatives thereof. The present invention further provides use of the compounds of the present invention in the treatment of bacterial infection and in the treatment of HIV infection. Also provided are pharmaceutical compositions comprising the compounds of the present invention. 

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Carlton, Australia

John Joseph Deadman