Other

Plas-pak Industries, Inc.

Siemens Medical Solutions Usa, Inc.

Patent Investment Corporation

Imi Vision Limited

Advanced Micro Devices Corporation

Bayer Aktiengesellschaft

Nordson Corporation

Bayer Pharma Aktiengesellschaft

Control Components, Inc.

Compugen Ltd. Corporation

Lumonics Inc.

Compview Medical, LLC

Thomsen Equipment Company

John J Hunter

Douglas P Goulet

Eugene V Stepanov

Albert I Lee

Brian Glass

Brent A Giansanti

Brian Dauphinais

Albert E Sandholm

Brian Lucas

David Hiebert Klassen, Sr

Greg Long

David Fitzgerald

Ofer Levy

Spencer Liang

Ilan Vaknin

Uwe Gritzan

Paul J Sokolovsky

Lars Röse

James L Hayward

Paul White

Richard W Clemens

Jon Zimmerman

Julia Hütter

Andrew Pow

Sunil Gupta

Eugene Stepanov

The present invention relates to a novel pharmaceutical combination comprising an ILDR2 antagonist according to any of the aforementioned claims, plus one or more other therapeutically active compounds, and to novel specific ILDR2 antagonists.

ILDR2 antagonists and combinations thereof

An applicator system for extrusive dispensing of work material from a flexible pre-charged portion of a cartridge unit is provided. The system comprises a body portion having an actuator and a housing coupled thereto. The housing includes a cartridge bay and an arresting member displaceably coupled thereto. The cartridge bay is configured to receive the cartridge unit and defines at least one containment compartment for receiving the pre-charged cartridge. The arresting member is displaceable between open and closed configurations for releasably retaining the cartridge unit. The actuator, coupled to the housing in communication with the cartridge bay, includes a drive member engaging the pre-charged cartridge within the containment compartment. The body includes a handle and an activation member coupled thereto. The activation member is coupled to the actuator to selectively activate displacement of the drive member within the containment compartment responsive to user manipulation thereby compressing the pre-charged cartridge therein.

Applicator system for extrusive dispensing of work material from collapsible cartridge

An interactive method of displaying information in an operating room can include receiving data via a reader from badges associated with persons to establish the presence of persons in the operating room or the like. The data can be processed and the identifying information can be displayed on a display device that is visually accessible within the operating room. The display device can also display other relevant information, including surgical pause checklists, retained object counts, and relevant medical data.

Interactive display for use in operating rooms

A valve trim for a pressure reduction valve containing a plurality of high hydraulic flow resistance flowpaths therethrough. Each flowpath comprises at least two inlets () and at least one impingement zone () having two zone inlets () and two zone outlets (). The zone inlets () communicate with the inlets () and are arranged substantially 180 degrees to one another. The two zone outlets () are arranged substantially perpendicular to the zone inlets () such that flow entering the two zone inlets () mutually impinges on itself creating an area of high energy loss, and thereafter separates and exits through the zone outlets ().

Fluid control

A valve having a trim comprising a plurality of a vortex flowpaths, each flowpath comprising a central vortex chamber and having three tangential inlet passages is provided. As the fluid flows through the inlet passages and enters the vortex chamber the flows start to turn and impinge upon one another, i.e., the flow entering via inlet passage will impinge upon the flow entering via inlet, the flow entering inlet will impinge on the flow entering inlet and the flow entering inlet will impinge on the flow entering inlet. As the flow entering vortex chamber impinges on another fluid flow as opposed to a wall of the flowpath the vortex can be used to create a flowpath with reduced erosion. The flow from the inlets combine in a radial flow within the vortex chamber and exit via the outlet which is substantially axial to the vortex chamber.

A valve having a trim comprising a plurality of impingement flowpaths, each flowpath comprising a central impingement chamber and having three radially directed inlet passages is provided. As the fluid floes through the inlet passages and enters the impingement chamber the flow starts to turn and impinge upon one another at a substantially central point within the impingement chamber and exit together via the outlet which is substantially axial to the impingement chamber. As the flows entering the impingement chamber impinge on one another as opposed to a wall of the flowpath, the impingement can be used to create a flowpath with reduced erosion.

A claim pre-processing system employs trial adjudication to improve claim accuracy prior to claim submission to a healthcare payer institution or other entity. A system processes claim data related to provision of healthcare to a patient The system includes a claim data collator for collating data related to a claim for a particular patient for submission to a payer and a source of rules for use in processing collated claim data. A pre-processor submits the collated claim data for processing using the rules to validate the collated claim data is in condition for processing to initiate generation of payment. A claim processor submits the collated claim data to a payer, in response to successful validation by the pre-processor. A rules processor processes acquired claim data to identify a condition triggering application of a different set of rules for determining validity of an individual claim element. The pre-processor re-submits amended collated claim data for processing using the rules to validate the collated claim data is in condition for processing to initiate generation of payment, the amended collated claim data being received in response to unsuccessful validation using the rules.

System for processing healthcare claim data

A patient claim data processing system responds to and initiates clinical events and attains early accurate claim data during a patient healthcare encounter cycle to support prompt claim data validation and editing both for individual claim elements and for a completed claim to improve claim accuracy prior to claim submission to a payer. The system submits accurate claims to payers and receives remittance advice from payers and applies rules to the advice. A system processes financial data related to provision of healthcare to a patient in response to clinical events. The system includes an interface processor for receiving a message identifying an event and a related change in healthcare data concerning a patient and also includes a source of rules for determining characteristics associated with reimbursement for provision of an individual service to a patient. A rules processor initiates application of a rule derived from the rules source to process financial data concerning provision of the individual service to the patient in response to receiving the message identifying the event. A result processor initiates an action in response to a result derived by the application of the rule to process the financial data. The rules processor also validates the financial data complies with the rule.

Healthcare financial data and clinical information processing system

A multi-cartridge powered dispenser includes a frame having base and top cartridge supports, wheels and a handle. A piston/cylinder is mounted on the frame and at least three cartridges are clamped between the support plates. Each cartridge has a shuttle at the lower end and a discharge opening at the upper end. The piston/cylinder assembly has push rods extending through the base support to move the shuttles in the cartridges. A pressurized fluid supply conduit is connected to the piston/cylinder, and a valve in the fluid supply conduit controls the flow. Discharge cannulae communicate with the outlets the cartridges. Discharge conduits extend between the cannulae and a handpiece for applying the contents of the cartridges to a work surface. The application handpiece can be a sprayer, a roller applicator, or a pour/extrude applicator.

Multi-cartridge dispenser

A disposable synthetic resin spray nozzle assembly for spraying reactive multi-component liquid mixtures includes a static mixer and an air or gas manifold. The static mixer has an elongated mixing tube containing a mixing element, and a liquid dispensing nozzle is formed at the downstream end of the mixing tube. A one-piece manifold has an inner wall which includes a mixer support section sealingly mounted around the static mixer, an air inlet section for receiving an air supply through a conduit, and an air dispensing section which, together with the outer wall of the liquid dispensing nozzle, forms an air dispensing nozzle. The reactive liquid mixture is atomized by air that supplied through the air dispensing nozzle.

Disposable spray nozzle assembly

A laser system (20) controlling laser pulse energy by feedback to the laser Q-switch (34) is disclosed. A feedback signal (40) is used to control the time duration of the high loss state of the Q-switch for automatically adjusting the output pulse energy to substantially equal an energy setpoint (84).

Laser system for controlling emitted pulse energy

A PGA integrated circuit package includes a package substrate (12), a unidirectional electrically conductive elastomeric layer (14), a plastic tape layer (16) having a centrally disposed chip (18), an insulator layer (20), and a cover member (22). A plurality of metal terminal pins (24) extend from a bottom surface of the substrate (12) and protrude slightly above a top surface thereof to form terminal pin ends (30). The elastomeric layer (14) is deposited over the substrate (12) for engagement with the terminal pin ends (30). The tape layer (16) and the chip (18) are deposited over the elastomeric layer (14). The tape layer (16) has a metalized trace pattern deposited on its bottom surface. The metalized trace pattern terminates at its outer ends with spaced apart metal terminal pads (32) which are in substantially vertical alignment with the respective terminal pin ends (30). The insulator layer (20) and the cover member (22) are compressed to establish electrical interconnection between the terminal pads and the respective terminal pin ends through the elastomeric layer (14).

Electrical connections via unidirectional conductive elastomer for pin

Disclosed is a method and apparatus for forming a pipe joint for securing lined pipe sections together. A portion of the liners of adjacent pipe sections are overlapped and compressed when the pipe joint is made up so as to seal against the migration of pressurized fluids from within the pipe sections.

Lined pipe joint

Disclosed is a pipe coupling joint comprising an interference fit coupling of unthreaded pipe sections. The end of the outer pipe in a telescoped interference fit coupling is radially compressed to form a groove in the inner pipe. The crimped end is compressed into the groove to securely couple the pipe sections together. Lined pipe joints and methods and apparatus for forming the improved interference fit joint are also disclosed.

Growing community of inventors

Abilene, TX, United States of America

John J Hunter