The Scripps Research Institute

Northwestern University

John J Friedewald

Sunil M Kurian

Michael Abecassis

Daniel R Salomon

Phillip T Ordoukhanian

Steve Head

Steven Robert Head

Josh Levitsky

This disclosure provides methods of detecting sub-acute rejection and other categories of rejection in kidney transplant recipients using unique sets of gene expression markers.

Genome-wide classifiers for detection of subacute transplant rejection and other transplant conditions

By a genome-wide gene analysis of expression profiles of over 50,000 known or putative gene sequences in peripheral blood, the present inventors have identified a consensus set of gene expression-based molecular biomarkers associated with subclinical acute rejection (subAR). These genes sets are useful for diagnosis, prognosis, monitoring of subAR.

Gene expression profiles associated with sub-clinical kidney transplant rejection

Disclosed herein are methods of detecting, predicting or monitoring a status or outcome of a transplant in a transplant recipient.

Methods and systems for analysis of organ transplantation

Growing community of inventors

Chicago, IL, United States of America

John J Friedewald