C. R. Bard, Inc.

Medtronics Ave, Inc.

John Hudson

Richard K Elton

Eugene Tedeschi

Stephen M Grantz

A two step method or process for improving the adherence or bonding of a lubricious coating of a crosslinked polyurethane, polyurea or polyurethaneurea/PEO or PVP coating to a substrate surface, said two step method comprising a first step of subjecting said surface to a surface preparation which results in the treated surface being provided with a functional tie layer containing functional groups for reaction with functional groups of a reaction mixture to be applied in a subsequent second step, which upon curing forms a crosslinked polyurethane, polyurea or polyurethaneurea/PEO or PVP coating and a second step of applying to said tie layer said reaction mixture and curing the reaction mixture. A medical device resulting from the above-described two step method.

Method of improving the adherence of certain crosslinked polymer coatings containing PEO or PVP to a substrate

A pressure-sensitive balloon catheter includes a material that undergoes a visible color change when exposed to the pressures experienced in an angioplasty or a stent placement procedure. By removing the balloon catheter and verifying the color change and the patterns of colors on the balloon, a physician can verify that proper amounts of pressure were applied to all portions of a patient's artery or a stent within a patient's artery.

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Wells, ME, United States of America

John Hudson