Kent State University

University of Chester

John Henry Howatson Williams

Nicola E Brasch

Catherine Stephanie Birch

Therapeutic applications, such as prevention, treatment and supplementation, for the use of novel and other thiolatocobalamins to protect human cells against the effects of oxidative stress. In particular, this invention relates to the use of a novel synthetic thiolatocobalamin, N-acetyl-L-cysteinylcobalamin (NACCbl) to protect animal cells against oxidative stress damage. This invention also relates to the use of thiolatocobalamins, such as NACCbl, in lieu of current, commercially available forms of vitamin Bfor the treatment and prevention of conditions associated with oxidative stress damage and for dietary supplementation.

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Corwen, United Kingdom

John Henry Howatson Williams