Acclarent, Inc.

Twelve, Inc.

Tusker Medical, Inc.

The Foundry, Inc.

Medtronic, Inc.

Foundry Innovation & Research 1, Ltd.

Foundry Therapeutics, Inc.

Coapt Systems, Inc.

Foundry Newco Xi, Inc.

Microaire Surgical Instruments, Inc.

Coapt LLC

Greg Lamps

Daniel Irvin Jacobs

Mark Senatori

John H. Morriss

John H Morriss

John Y Chang

Joshua Makower

Hanson Gifford

Ketan P Muni

Hung V Ha

Julia D Vrany

William M Facteau

Eric A Goldfarb

Matt McLean

Isaac J Kim

Greg Liu

Mark E Deem

Jean-Pierre Dueri

Thomas R Jenkins

Anton G Clifford

Hanson S Gifford, Iii

Michael Luna

Amrish Jayprakash Walke

Rohit Kulbhushan Girotra

James I Fann

Jeffry J Grainger

Bernard H Andreas

Darin Charles Gittings

Jeffrey Allen Walker

William E Bolger

Randy S Chan

David Jerry Scott

David Trask

Nga K Van

Kate Hames

Honglei Wang

Koon Kiat Teu

Jingnan Luo

Maureen Bensing

Katie Miyashiro

Kirsten Valley

Douglas Sutton

Richard Roy Newhauser, Jr

Scott J Baron

Mei Y Pader

Paul G Hayter

Matt Mclean

Earl A Bright, Ii

Carlos F Fernandez

Joseph Roberson

Rohit Girotra

Bryan Dale Knodel

Cary J Reich

Douglas S Sutton

Philip Christopher Evard

Tom Thanh Vo

Thomas Daniel Gross

Richard R Newhauser, Jr

Michael J Hendricksen

Erik James Shahoian

Mark Y Hirotsuka

Mathew D Clopp

Robert N Wood

Greg Miller

Jeffrey J Grainger

Gregory Liu

Hanson S Gifford

Martin L Mayse

Joshua J Dwork

Finn Olavi Rinne

Daniel Jacobs

Karun D Naga

Robert J Elson

Vijaykumar Rajasekhar

Daniel Boon Lim Seet

Wei Li Lee

Stephen W Boyd

David Grossman

Thomas E Jenkins

Matthew D Clopp

James L Fann

Darrin Gittings

Julie D Vrany

Nathaniel Piland

William J Facteau

Bryan Knodel

Melissa Davis

Hanson Iii Gifford

Iii Hanson S Gifford

Mark Deem

Hanson S Iii Gifford

A heart valve repair device may include a support configured to extend through a native annulus of a native heart valve, wherein the support comprises an upstream portion and a downstream portion; an annular expandable retainer extending from the upstream portion of the support, and an arm extending from the downstream portion of the support. The annular expandable retainer may include a C-shaped cross-section that is open inwardly. The arm may be configured to reach behind a leaflet of the native heart valve and sandwich the leaflet between the arm and the support.

Devices, systems and methods for heart valve replacement

The devices, systems, and methods disclosed herein may be directed to a delivery system including a therapeutic member configured for endoluminal placement via the delivery system into the esophagus of the patient, wherein the therapeutic member comprises a treatment portion comprising a film for controlled release of a chemotherapeutic agent. The film may comprise a control region, a therapeutic region, and a substantially impermeable base region. The film is configured to release the chemotherapeutic agent in a direction away from the substantially impermeable base region. The delivery system is configured to enable a treatment provider to position the treatment portion of the therapeutic member proximate to a treatment site associated with the esophagus of the patient, and the therapeutic member is configured to administer a therapeutically effective dose to the treatment site for a sustained period following endoluminal placement of the therapeutic member.

Devices, systems, and methods for treating intraluminal cancer via controlled delivery of therapeutic agents

Systems for mitral valve repair are disclosed where one or more mitral valve interventional devices may be advanced intravascularly into the heart of a patient and deployed upon or along the mitral valve to stabilize the valve leaflets. The interventional device may also facilitate the placement or anchoring of a prosthetic mitral valve implant. The interventional device may generally comprise a distal set of arms pivotably and/or rotating coupled to a proximal set of arms which are also pivotably and/or rotating coupled. The distal set of arms may be advanced past the catheter opening to a subannular position (e.g., below the mitral valve) and reconfigured from a low-profile delivery configuration to a deployed securement configuration. The proximal arm members may then be deployed such that the distal and proximal arm members may grip the leaflets between the two sets of arms to stabilize the leaflets.

System for mitral valve repair and replacement

Systems, apparatuses, and methods for treating native heart valves are disclosed herein. A system for delivering a prosthetic device into a heart of a patient includes an elongated catheter body and a delivery capsule. The delivery capsule can be hydraulically driven to deploy at least a portion of a prosthetic heart valve device. The delivery capsule can release the prosthetic heart valve device at a desired treatment site in a patient.

Hydraulic delivery systems for prosthetic heart valve devices and associated methods

A method of anesthetizing a tympanic membrane of an ear of a patient using iontophoresis is disclosed. The method involves delivering an anesthetizing drug solution to an ear canal of the patient's ear, wherein the drug solution includes an anesthetic and a buffer, and wherein the drug solution has a pH in a range of about 6.5 to about 7.5; and applying an amount of current to the drug solution, wherein the applied amount of current is increased at a rate of less than about 0.5 milliamp per second until a maximum current is achieved.

Iontophoresis methods

Methods and apparatus for treating disorders of the ear, nose, throat or paranasal sinuses, including methods and apparatus for dilating ostia, passageways and other anatomical structures, endoscopic methods and apparatus for endoscopic visualization of structures within the ear, nose, throat or paranasal sinuses, navigation devices for use in conjunction with image guidance or navigation system and hand held devices having pistol type grips and other handpieces.

Methods and apparatus for treating disorders of the ear nose and throat

Prosthetic heart valve devices for percutaneous replacement of native heart valves and associated systems and method are disclosed herein. A prosthetic heart valve device configured in accordance with a particular embodiment of the present technology can include an expandable support having an outer surface and configured for placement between leaflets of the native valve. The device can also include a plurality of asymmetrically arranged arms coupled to the expandable support and configured to receive the leaflets of the native valve between the arms and the outer surface. In some embodiments, the arms can include tip portions for engaging a subannular surface of the native valve.

Prosthetic heart valve devices and associated systems and methods

Prosthetic heart valve devices for percutaneous replacement of native heart valves and associated systems and method are disclosed herein. A prosthetic heart valve device configured in accordance with a particular embodiment of the present technology can include an anchoring member having an upstream portion configured to engage with tissue on or near the annulus of the native heart valve and to deform in a non-circular shape to conform to the tissue. The device can also include a mechanically isolated valve support coupled to the anchoring member and configured to support a prosthetic valve. The device can further include an atrial extension member extending radially outward from the upstream portion of the anchoring member and which is deformable without substantially deforming the anchoring member. In some embodiments, the upstream portion of the anchoring member and the extension member may be deformed while the valve support remains sufficiently stable.

Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods

Sinusitis and other disorders of the ear, nose and throat are diagnosed and/or treated using minimally invasive approaches with flexible or rigid instruments. Various methods and devices are used for remodeling or changing the shape, size or configuration of a sinus ostium or duct or other anatomical structure in the ear, nose or throat; implanting a device, cells or tissues; removing matter from the ear, nose or throat; delivering diagnostic or therapeutic substances or performing other diagnostic or therapeutic procedures. Introducing devices (e.g., guide catheters, tubes, guidewires, elongate probes, other elongate members) may be used to facilitate insertion of working devices (e.g. catheters e.g. balloon catheters, guidewires, tissue cutting or remodeling devices, devices for implanting elements like stents, electrosurgical devices, energy emitting devices, devices for delivering diagnostic or therapeutic agents, substance delivery implants, scopes etc.) into the paranasal sinuses or other structures in the ear, nose or throat, Specific devices (e.g., tubular guides, guidewires, balloon catheters, tubular sheaths) are provided as are methods for manufacturing and using such devices to treat disorders of the ear, nose or throat.

Devices, systems and methods useable for treating sinusitis

Growing community of inventors

Portola Valley, CA, United States of America

John H Morriss