American Cyanamid Company

John H Martin

Donald B Borders

Raymond T Testa

Martin R Hertz

Raymond C Yao

David P Labeda

May D Lee

Joseph J Goodman

Amedeo A Fantini

Jane P Kirby

Homer D Tresner

Joseph D Korshalla

John Norman Porter

This invention relates to new polypeptide antibiotics designated LL-BO2964.alpha., LL-BO2964.beta., LL-BO2964.gamma., and a mixture thereof designated LL-BO2964, produced during microbiological fermentation, under controlled conditions, using a new strain of Streptomyces coeruleorubidus subspecies rubidus or a mutant thereof. The new antibiotics are active against a variety of microorganisms and are also useful in treating tuberculosis.

Antibiotic agents from S. coeruleorubidus, rubidus

This invention relates to two new antibacterial and anti-tumor agents designated LL-BO1208.alpha. and LL-BO1208.beta. produced during microbiological fermentation, under controlled conditions, using the novel microorganism Streptoverticillium stramineum and mutants thereof.

Antibiotic LL-BO1208.alpha. and LL-BO1208.beta., process of preparation,

This invention relates to a novel process for the production of antibiotic X-14868A using the novel microorganism Antinomadura yumaense sp. nov.

Process for producing antibiotic X-14868A

This disclosure describes a novel process for the production of the known antibiotic nosiheptide using a new strain of Streptomyces glaucogriseus and mutants thereof.

Process for producing the antibiotic nosiheptide

This disclosure describes a new antibiotic designated BL580.DELTA. produced in a microbiological fermentation under controlled conditions using a new strain of Streptomyces hygroscopicus and mutants thereof. This new antibiotic is an active anticoccidial agent.

Process of producing antibiotic BL580.DELTA. with Streptomyces

Antibiotic BL580.DELTA. and method of use

This disclosure describes a new antibiotic designated BL580 ZETA produced in a microbiological fermentation under controlled conditions using a new strain of Streptomyces hygroscopicus and mutants thereof. This new antibiotic is an active anticoccidial agent.

Antibiotic BL580 Zeta and use thereof as anticoccidial agent

This disclosure describes 5 new antibacterial agents designated BM123.alpha., BM123.beta. .sub.1, BM123.beta..sub.2, BM123.gamma..sub.1, and BM123.gamma..sub.2 produced in a microbiological fermentation under controlled conditions using a new strain of an undetermined species of Nocardia and mutants thereof. The new antibacterial agents are active against a variety of microorganisms and thus are useful in inhibiting the growth of such bacteria wherever they may be found.

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New City, NY, United States of America

John H Martin