Lehigh University

Puritek, Inc.

John H Abel

Barbara Obrepalska-Bielska

Gary E McQuay

Sue Ellen Slezak

Kathy L Gottlund

Ronald Walter Krumm

Eugene A Nau

A portable apparatus for decontaminating water, having an iodine release section in which iodine, often from a charged nylon iodophor, is released into the water, followed by an iodine recapture section in which a nylon polymer removes iodine from the water by forming an iodophor with it.

Liquid purification apparatus

The present invention provides methods and reagents for assessing lipoprotein metabolism. The methods provided are applicable for use on multiple samples in a clinical laboratory, thus obviating the need for sophisticated instrumentation, such as flow cytometry. Selected cell types in a test sample are uniformly labelled with a detectable reporter substance, so that they may later be enumerated. Pre-determined lipoprotein receptors associated with the cells of interest are labelled with a receptor-selective marker, thereby to determine the number of lipoprotein receptors per cell in the test sample. Selected cells of interest are conveniently separated from the test sample by binding thereto a specific binding substance attached to a solid support. The specific binding substance binds specifically with a characteristic determinant of the cell subset of interest. The remainder of the test sample may be washed away or discarded. The separated cells of interest may then be enumerated by measuring the amount of detectable label associated therewith, hence to determine the number of lipoprotein receptors per cell in each test sample.

Method and reagents for assessing lipoprotein metabolism

Two diagnostic methods for evaluating LDL mechanism in a patient are disclosed. A novel diagnostic agent for evaluating LDL metabolism comprising a ligand capable of binding LDL receptors and a fluorescent label and a diagnostic kit for evaluating LDL metabolism which utilized the specified diagnostic agent are also disclosed.

Methods for evaluating cholesterol metabolism and reagents therefor

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Bethlehem, PA, United States of America

John H Abel