St. Jude Medical Ab

John Gustafsson

Nils Holmström

Sven-Erik Hedberg

Andreas Blomqvist

Michael Broome

Andreas Karlsson

An implantable medical device, IMD, () is connectable to at least one ventricular lead () having a ventricular basal electrode () and a ventricular apical electrode (). The IMD () comprises a pulse generator () for generating pacing pulses applied to a heart () through the ventricular lead (). The operation of this pulse generator () is controlled by a controller () that is configured to control the pulse generator to first deliver a pacing pulse to the ventricular basal electrode () to stimulate the basal portion of the ventricle () before a pacing pulse is delivered to the apical portion of the ventricle () by the ventricular apical electrode (). This pulse sequence achieves a biologically more correct cardiac stimulation and a contraction pattern that reduces the risk for valvular regurgitation.

Implantable medical device for cardiac therapy

An implantable medical device applies an electric signal over two electrodes and measures the resulting electric signal over a candidate pair of neighboring electrodes on a lead for a first heart ventricle or over a candidate electrode of the lead and a case electrode. An impedance signal is determined for each candidate pair or electrode based on the applied signal and the measured resulting signal. A time difference between start of contraction in a second ventricle and the timing of local myocardial contraction as identified from the impedance signal at the site of the candidate pair or electrode is determined for each candidate pair or electrode. An optimal pacing electrode is selected to correspond to one of the electrodes of the candidate pair having the largest time difference or the candidate electrode having largest time difference.

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Hagersten, Sweden

John Gustafsson