Intermolecular, Inc.

Symyx Technologies, Inc.

John Gallipeo

Eric D Carlson

Leonid Matsiev

Lynn Van Erden

Oleg Kolosov

Anthony F Volpe

H Sam Bergh

Jason Wells

Mikhail Spitkovsky

Laura T Mazzola

Victor Wong

Jeffrey Maag

The present invention discloses an apparatus and method for rapid analysis of members of a combinatorial library. The apparatus includes a plurality of reactor vessels for containing individual library members, a fluid handling system that apportions a test fluid about equally between each of the vessels and a housing for enclosing the reactor vessels, the housing defining a pressure chamber, wherein the housing is configured to sustain a pressure substantially above atmospheric pressure. This allows for simultaneous screening of library members at high pressure by providing a small pressure differential on reactor components. The disclosed apparatus is especially useful for screening library members based on their ability to catalyze the conversion of fluid reactants.

High pressure parallel fixed bed reactor and method

A method and apparatus for measurement of mass of small sample sizes. The method and apparatus is particularly adapted for providing microbalance measurement of solid materials as part of a combinatorial research program. The method and apparatus contemplate monitoring the response of a resonator holding a sample and correlating the response with mass change in the samples.

High throughput microbalance and methods of using same

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Morgan Hill, CA, United States of America

John Gallipeo