Thermo Finnigan LLC

John G Voss

Scott T Quarmby

George B Guckenberger

Giacinto Zilioli

Dustin J Kreft

Nathaniel L Sanders

Charles H Vogt

Michael B Young

A tuning system may acquire, from a mass spectrometer during a batch of one or more analytical runs performed with the mass spectrometer, tune data associated with an operating characteristic of the mass spectrometer. The tuning system may determine, based on the tune data, a value of an operating parameter configured to adjust the operating characteristic of the mass spectrometer and set the operating parameter to the determined value.

Methods and systems for tuning a mass spectrometer

A method of operating a mass spectrometer comprising: detecting a first ion species using a first gain setting of a detector or a first emission current for a first mass-to-charge range; detecting a second ion species using a second gain setting of the detector or a second emission current for a second mass-to-charge range; and using the detected first and second ion species to calibrate the mass range of a mass analyzer of the mass spectrometer, to tune the resolution of the mass analyzer, or to tune an ion optic of the mass spectrometer.

Reducing detector wear during calibration and tuning

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Round Rock, TX, United States of America

John G Voss